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作者:... Franç , ois Lanza , Christian Gachet
来源:[J].Thromb Haemost(IF 6.094), 2017, Vol.117 (6), pp.1101-1114Schattauer 出版社
摘要:The combined action of collagen and thrombin induces the formation of COAT platelets, which are characterised by a coat of procoagulant and adhesive molecules on their surface. Although recent work has started to highlight their clinical relevance, the exact mechanisms regulating...
作者:ois Lanza , Christian Gachet
来源:[J].Thromb Haemost(IF 6.094), 2015, Vol.114 (6), pp.1175-1188Schattauer 出版社
摘要:The ability of cellular fibronectin, found in the vessel wall in a fibrillar conformation, to regulate platelet functions and trigger thrombus formation remains largely unknown. In this study, we evaluated how parietal cellular fibronectin can modulate platelet responses under fl...
作者:... Edith Fressinaud , Franç , ois Lanza
来源:[J].Thromb Haemost(IF 6.094), 2016, Vol.116 (6), pp.1070-1078Schattauer 出版社
摘要:Interaction between von Willebrand factor (VWF) and platelet GPIbα is required for primary haemostasis. Lack or loss-of-function in the ligand-receptor pair results in bleeding complications. Paradoxically, gain-of-function mutations in VWF or GPIbα also result in ble...

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