全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Zixuan Liu , Yonglan Zhang ...
来源:[J].Archives of Pharmacal Research(IF 1.538), 2017, Vol.40 (5), pp.571-578Springer
摘要:An large body of evidence indicates that leptin has protective role against Alzheimer’s disease, where it reduces β-amyloid (Aβ) production in both cell culture and animal models. Our previous studies revealed that geniposide could attenuate the production of Aβ1–4...
作者:Zixuan Liu , Yonglan Zhang
来源:[J].Indian Journal of Medical Research(IF 2.061), 2015, Vol.142 (2), pp.190-195DOAJ
摘要:Background & objectives: Amyloid β-peptide (Aβ) has been shown to be responsible for senile plaque formation and cell damage in Alzheimer′s disease (AD). This study was aimed to explore the role of natural compound icariin on the aggregation and the cytotoxicity of Aβ i...
作者:Zixuan Liu , Runhai Jiao
来源:[J].Energies(IF 1.844), 2019, Vol.12 (9)DOAJ
摘要:In a real interactive service system, a smart meter can only read the total amount of energy consumption rather than analyze the internal load components for users. Nonintrusive load monitoring (NILM), as a vital part of smart power utilization techniques, can provide load disagg...
作者:Zixuan Liu , Danwei Yu ...
来源:[J].Viruses(IF 2.509), 2019, Vol.11 (7)DOAJ
摘要:Entry of HIV-1 into target cells is mediated by its envelope (Env) glycoprotein composed of the receptor binding subunit gp120 and the fusion protein gp41. Refolding of the gp41 N- and C-terminal heptad repeats (NHR and CHR) into a six-helix bundle (6-HB) conformation drives the ...
作者:Zixuan Liu , Jizhou Zhang ...
来源:[J].Electronic Journal of Biotechnology(IF 0.827), 2015, Vol.18 (4), pp.302-306Elsevier
摘要:Abstract(#br)Background(#br)Overexpression or mutated activation of Fibroblast growth factor receptor 3 (FGFR3) is involved in the pathogenesis of many tumors. More and more studies focus on the potential usage of therapeutic antibodies against FGFR3.(#br)Results(#br)In this...
作者:... Yonglan Zhang , Zixuan Liu , Yanwen Wang
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (10)DOAJ
摘要:Glucose-stimulated insulin secretion (GSIS) is essential to the control of metabolic fuel homeostasis. The impairment of GSIS is a key element of β-cell failure and one of causes of type 2 diabetes mellitus (T2DM). Although the KATP channel-dependent mechanism of GSIS has be...
作者:Zixuan Liu , Dandan Liu ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2018, Vol.49 (3), pp.1151-1167DOAJ
摘要:Background/Aims: Swine influenza virus (SIV) is a major pathogen of both animals and humans. Afatoxin B1 (AFB1) is one of the most common mycotoxins in feed and food. However, the central contribution of AFB1 to SIV infection remains unclear. Methods: Here, TCID50 assays, fl...
作者:Zixuan Liu , Yonglan Zhang
来源:[J].Indian Journal of Medical Research(IF 2.061), 2015, Vol.142 (2), pp.190-195Wolters Kluwer
摘要:Background & objectives: Amyloid β-peptide (Aβ) has been shown to be responsible for senile plaque formation and cell damage in Alzheimer′s disease (AD). This study was aimed to explore the role of natural compound icariin on the aggregation and the cytotoxicity of Aβ i...
作者:Zixuan Liu , Yawen Wang ...
来源:[J].Toxicology(IF 4.017), 2016, Vol.363-364, pp.48-57Elsevier
摘要:Abstract(#br)Our previous studies demonstrated that tetrachlorobenzoquinone (TCBQ), an active metabolite of pentachlorophenol, has effects on the generation of reactive oxygen species (ROS) and oxidative stress in vitro and in vivo . Nuclear factor erythroid-derived 2-like 2 (Nrf...

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