全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Zhining Wen , Zhibin Liu ...
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer
摘要:TEs pervade mammalian genomes. However, compared with mice, fewer studies have focused on the TE expression patterns in rat, particularly the comparisons across different organs, developmental stages and sexes. In addition, TEs can influence the expression of nearby genes. The te...
作者:... Qifan Kuang , Zhining Wen , Menglong Li
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (14)Springer
摘要:Endometrial cancers (ECs) are one of the most common types of malignant tumor in females. Substantial efforts had been made to identify significantly mutated genes (SMGs) in ECs and use them as biomarkers for the classification of histological subtypes and the prediction of clini...
作者:Zhining Wen , Xianyang Luo ...
来源:[J].BMC Cancer(IF 3.333), 2015, Vol.15 (1)Springer
摘要:Abstract(#br) Background(#br)It is difficult for the parotid gland neoplasms to make an accurate preoperative diagnosis due to the restriction of biopsy in the parotid gland neoplasms. The aim of this study is to apply the surface-enhanced Raman spectroscopy (SERS) method fo...
作者:Zhining Wen , Jiamin Xiao ...
来源:[J].BMC Bioinformatics(IF 3.024), 2011, Vol.12 (1)Springer
摘要:Abstract(#br) Background(#br)The rapid accumulation of data on non-synonymous single nucleotide polymorphisms (nsSNPs, also called SAPs) should allow us to further our understanding of the underlying disease-associated mechanisms. Here, we use complex networks to study the role o...
作者:Zhining Wen , Hui Yin ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.6 (3)DOAJ
摘要:Owing to their potential for systematic analysis, complex networks have been widely used in proteomics. Representing a protein structure as a topology network provides novel insight into understanding protein folding mechanisms, stability and function. Here, we develop a new feat...
作者:Zhining Wen , Yu Liang ...
来源:[J].Drug Discovery Today(IF 6.551), 2018Elsevier
摘要:Drug-induced rhabdomyolysis (DIR) is an idiosyncratic and fatal adverse drug reaction (ADR) characterized in severe muscle injuries accompanied by multiple-organ failure. Limited knowledge regarding the pathophysiology of rhabdomyolysis is the main obstacle to developing early bi...
作者:... Menglong Li , Guoquan Hu , Zhining Wen
来源:[J].Computational Biology and Chemistry(IF 1.793), 2017Elsevier
摘要:Abstract(#br)Dysregulated and reprogrammed metabolism is one of the most important characteristics of cancer, and exploiting cancer cell metabolism can aid in understanding the diverse clinical outcomes for patients. To investigate the differences in metabolic pathways among pati...
作者:Zhining Wen , Haitian Wang ...
来源:[J].The AAPS Journal(IF 4.386), 2013, Vol.15 (3), pp.884-892Springer
摘要:Abstract(#br)The current study utilized a combined pharmacokinetic and genomic approach to demonstrate the feasibility of a new quality control method by using a panel of special differentially expressed genes (DEGs) as unique fingerprint to serve as marker of in vivo bioact...
作者:... Menglong Li , Zhining Wen , Li He
来源:[J].Computational Biology and Chemistry(IF 1.793), 2014, Vol.49, pp.71-78Elsevier
摘要:Abstract(#br)Estrogen receptor status and the pathologic response to preoperative chemotherapy are two important indicators of chemotherapeutic sensitivity of tumors in breast cancer, which are used to guide the selection of specific regimens for patients. Microarray-based gene e...
作者:... Keqin Liu , Menglong Li , Zhining Wen
来源:[J].Chemometrics and Intelligent Laboratory Systems(IF 2.291), 2015, Vol.146, pp.464-471Elsevier
摘要:Abstract(#br)In clinical research, DNA microarrays are widely applied in the identification of the oncogenes, which are differentially expressed between two clinical states and considered as predictors for the cancer prognosis. Due to the heterogeneity of clinical samples, t...

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