全部文献期刊会议图书|学者科研项目
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作者:... Wei Zhang , Zhao-Qian Liu , Hong-Hao Zhou
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)
摘要:Colon cancer (CC) is a heterogeneous disease influenced by complex gene networks. As such, the relationship between networks and CC should be elucidated to obtain further insights into tumour biology.
作者:... Hong-Hao Zhou , Ji-Ye Yin , Zhao-Qian Liu
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)
摘要:Epigenetic alterations are strongly associated with the development of cancer. The aim of this study was to identify epigenetic pattern in squamous cell lung cancer (LUSC) on a genome-wide scale.
作者:... Xi Li , Hong-Hao Zhou , Zhao-Qian Liu
来源:[J].Cancer Letters(IF 4.258), 2018, Vol.415, pp.49-57
摘要:Abstract(#br)Accumulating evidence has shown that lncRNAs and circRNAs are novel regulators of gene expression. The discovery of numerous lncRNAs and circRNAs, and investigation into their structures and functions will contribute to our understanding of the pathogenesis of diseas...
作者:... Wei Zhang , Hong-Hao Zhou , Zhao-Qian Liu
来源:[J].Cancer Letters(IF 4.258), 2018, Vol.412, pp.81-87
摘要:Abstract(#br)eIF3a is the largest subunit of eIF3, which is a key player in all steps of translation initiation. During the past years, eIF3a is recognized as a proto-oncogene, which is an important discovery in this field. It is widely reported to be correlated with cancer occur...
作者:... Cheng Peng , Hong-Hao Zhou , Zhao-Qian Liu
来源:[J].Journal of Affective Disorders(IF 3.295), 2017, Vol.215, pp.94-101
摘要:Abstract(#br)Background(#br)New conceptualizations of depression have emphasized the role of the kynurenine pathway (KP) in the pathogenesis of postpartum depressive symptoms (PDS). Kynurenine 3-monooxygenase (KMO) is a rate-limiting enzyme of the KP, where it catalyzes the ...
作者:Zhao-Qian Liu , Hong-Hao Zhou
来源:[J].Neurochemistry International(IF 2.659), 2018, Vol.118, pp.34-41
摘要:Abstract(#br)The 12/15-lipoxygenase (12/15-LOX) enzymes react with polyunsaturated fatty acids producing active lipid metabolites that are involved in plethora of human diseases including neurological disorders. A great many of elegant studies over the last decades have contribut...
作者:... Wei Zhang , Hong-Hao Zhou , Zhao-Qian Liu
来源:[J].Brain Research(IF 2.879), 2019, Vol.1719, pp.30-39
摘要:Abstract(#br)Schizophrenia is known to be a complex and disabling psychiatric disorder. Dopamine receptor antagonists have a significant therapeutic effect in improving the positive symptoms that are associated with the illness. Therefore, dopamine receptor antagonists are c...
作者:... Ying-Chun Zhao , Hong-Hao Zhou , Zhao-Qian Liu
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (6)
摘要:AIM: To determine the pharmacogenetics of platinum-based chemotherapy in Non Small Cell Lung Cancer (NSCLC) patients. METHODS: Publications were selected from PubMed, Cochrane Library and ISI Web of Knowledge. A meta-analysis was conducted to determine the association between gen...
作者:... Wei Zhang , Hong-Hao Zhou , Zhao-Qian Liu
来源:[J].Clinical Lung Cancer(IF 2.038), 2015, Vol.16 (4), pp.298-304.e2
摘要:Abstract(#br)Background(#br)Platinum-based chemotherapy is the main treatment method for lung cancer patients. The genetic polymorphisms of Wnt-inducible signaling pathway protein 1 ( WISP1 ) were reported to be associated with the development of diverse lung diseases. In th...
作者:... Gao-Yun Hu , Zhao-Qian Liu , Dai Li
来源:[J].European Journal of Pharmacology(IF 2.592), 2016, Vol.773, pp.42-50
摘要:Abstract(#br)Fluorofenidone is a novel derivative of l -mimosine. It has remarkable anti-fibrotic properties. In this study, we established that fluorofenidone ameliorates pulmonary fibrosis (PF) both in vivo and in vitro by specifically inhibiting the expression of eukaryot...

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