全部文献期刊会议图书|学者科研项目
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作者:Zhang Chen-Guang , Bai Yan-Hua ...
来源:[J].Cell death & disease(IF 6.044), 2019, Vol.10 (2), pp.33
摘要:ISL1, a LIM-homeodomain transcription factor, serves as a biomarker of metastasis in multiple tumors. However, the function and underlying mechanisms of ISL1 in gastric cancer (GC) have not been fully elucidated. Here we found that ISL1 was frequently overexpressed in GC FFPE sam...
作者:Zhang Xiao-Chen , Zhang Chen-Guang ...
来源:[J].Journal of immunology research, 2018, Vol.2018, pp.1027323
摘要:We performed a systematic review and meta-analysis to determine the risk of immune-related pancreatitis associated with the treatment by immune checkpoint inhibitors (ICIs) for solid tumors. Eligible studies were selected from multiple databases including phase II/III randomized ...
作者:Zhang Chen-Guang , Gong Ming-Tao ...
来源:[J].FEBS open bio, 2016, Vol.6 (7), pp.707-19
摘要:Decorin (DCN) is a major member of the small leucine-rich proteoglycan (SLRP) family that is critically involved in tumorigenesis and the development of metastasis of cancers, including glioma. Overexpression of DCN was indicated to suppress glioma cell growth. However, the ...
作者:Zhang Feng-Lan , Shi Wen-Jie ...
来源:[J].PloS one(IF 3.73), 2015, Vol.10 (6), pp.e0129013
摘要:The technology of virus-based genetic modification in tissue engineering has provided the opportunity to produce more flexible and versatile biomaterials for transplantation. Localizing the transgene expression with increased efficiency is critical for tissue engineering as ...
作者:Zhang Qun-Mei , Di Wen-Yu ...
来源:[J].International journal of clinical and experimental pathology(IF 2.242), 2015, Vol.8 (5), pp.5224-9
摘要:INTRODUCTION(#br)MicroRNAs (miRNAs) play important roles in tumorigenesis. In this study, we investigated the role of miR-221 in the development and progression of clear cell renal cell carcinoma (ccRCC).(#br)METHODS(#br)Quantitative real-time PCR (qRT-PCR) was used to measure th...
作者:Zhang Xin-Zhong , Zhang Chen-Guang ...
来源:[J].Oncotarget(IF 6.636), 2015, Vol.6 (29), pp.26971-81
摘要:Glioma is a most common type of primary brain tumors. Extracellular vesicles, in the form of exosomes, are known to mediate cell-cell communication by transporting cell-derived proteins and nucleic acids, including various microRNAs (miRNAs). Here we examined the cerebrospinal fl...
作者:Zhang Chen-Guang , Wang Hui ...
来源:[J].Asian Pacific journal of cancer prevention : APJCP, 2013, Vol.14 (1), pp.359-65
摘要:The high mobility group box 1 (HMGB1) protein is a multifunctional cytokine-like molecule that plays an important role in the pathogenesis of tumors. In this study, real-time polymerase chain reactions and Western blot assays indicated that HMGB1 transcriptional activity and...
作者:... Xing Tian-Yu , Zhang Chen-Guang , Ding Wei
来源:[J].Current pharmaceutical design, 2014, Vol.20 (11), pp.1604-13
摘要:Nicotinamide phosphoribosyl transferase (Nampt) is the rate-limiting enzyme for the salvage biosynthesis of nicotinamide adenine dinucleotide (NAD). Although elevated level of Nampt expression has been observed in various cancers, the involvement of Nampt promoter regulation...
作者:Zhang Chen-guang , Guo Ya-jie
来源:[J].PloS one(IF 3.73), 2013, Vol.8 (7), pp.e67816
摘要:A susceptibility locus for tuberculosis, a re-emerging infectious disease throughout the world, was previously discovered to exist on chromosome 11p15. IFITM3 gene encoding for interferon inducible transmembrane protein 3, is located at 11p15. It acts as an effector molecule for ...
作者:Zhang Chen-Guang , Luo Yang-Hui
来源:[J].Acta crystallographica. Section E, Structure reports online(IF 0.347), 2012, Vol.68 (Pt 1), pp.o188
摘要:In the title compound, C(9)H(6)ClNO, the Cl atom deviates by 0.142 (1) Å from the quinoline ring mean plane (r.m.s. deviation = 0.013 Å). In the crystal, N-H⋯O hydrogen bonds link the mol-ecules into [010] C(4) chains. Aromatic π-π stacking inter-actions [shortest centr...

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