全部文献期刊会议图书|学者科研项目
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作者:Yury Tsoy , Jan Persson
来源:[J].Source Code for Biology and Medicine, 2017, Vol.12 (1)
摘要:Despite the broad use of FRET techniques, available methods for analyzing protein-protein interaction are subject to high labor and lack of systematic analysis. We propose an open source software allowing the quantitative analysis of fluorescence lifetime imaging (FLIM) while int...
作者:Yury Tsoy , Yong-Jun Kwon
来源:[J].Computational Biology and Chemistry(IF 1.793), 2015, Vol.58, pp.192-198
摘要:Abstract(#br)Although image-based phenotypic assays are considered a powerful tool for siRNA library screening, the reproducibility and biological implications of various image-based assays are not well-characterized in a systematic manner. Here, we compared the resolution of hig...
作者:Thuy Tuong Nguyen , Yury Tsoy
来源:[J].Statistical Papers(IF 0.683), 2017, Vol.58 (1), pp.211-225
摘要:Abstract(#br)We provide a data classification mechanism with missing data handling based on kernel partial least squares (kernel PLS) and discriminant analysis (kernel PLSDA). The novelty of the method is that class variables are used for validation of the missing values imputati...
作者:Yury Tsoy , Jin Yeop Kim ...
来源:[J].Source Code for Biology and Medicine, 2014, Vol.9 (5), pp.870-876
摘要:Abstract(#br)Background and method(#br)Successfully automated sigmoidal curve fitting is highly challenging when applied to large data sets. In this paper, we describe a robust algorithm for fitting sigmoid dose-response curves by estimating four parameters (floor, window, s...
作者:Yury Tsoy
来源:[C].Electronic Imaging2015
摘要:High-Content Screening (HCS) is a powerful technology for biological research, which relies heavily on thecapabilities for processing and analysis of cell biology images. The quality of the quantification results, obtainedby analysis of hundreds and thousands of images, is crucia...

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