全部文献期刊会议图书|学者科研项目
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作者:Yuning Liao , Ningning Liu ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)
摘要:Ovarian carcinoma is one of the most aggressive gynecological malignant neoplasms and makes up 25–30% of all cancer cases of the female genital tract. Currently, resistance to traditional chemotherapy is a great challenge for patients with Epithelial ovarian cancer (EOC). Th...
作者:Yuning Liao , Fangcheng Zhang ...
来源:[J].European Journal of Pharmacology(IF 2.592), 2019, Vol.846
摘要:Abstract(#br)Auranofin (Aur) inhibits thioredoxin reductases and is also an inhibitor of 19 S proteasome associated deubiquitinases, targeting USP14 and UCHL5. Androgen receptor is often over-expressed in prostate cancer (PCa) and is strongly linked to PCa growth and progression....
作者:Yuning Liao , Chuyi Huang ...
来源:[J].Cancer Letters(IF 4.258), 2019, Vol.465, pp.118-128
摘要:Abstract(#br)Breast cancer is the most common malignancy in women around the world. Estrogen receptor α (ERα) is expressed in approximately 70% of breast tumors, and considered as one of most effective targets in breast cancer therapy. It has been reported that the degradati...
作者:Yuning Liao , Zhiqiang Guo ...
来源:[J].European Journal of Pharmacology(IF 2.592), 2019, Vol.856
摘要:Abstract(#br)EGF receptor tyrosine kinase inhibitors (EGFR-TKIs) have been widely used as a standard therapy in non-small cell lung cancer (NSCLC) patients with EGFR mutations. However, most if not all of the patients who initially have responded to EGFR-TKIs later experience pro...
作者:Yuning Liao , Xiaohong Xia ...
来源:[J].Oncogene(IF 7.357), 2018, Vol.37 (14), pp.1896-1910
摘要:Abstract(#br)It has been well known that androgen receptor (AR) is critical to prostate cancer development and progression. It has also been documented that AR is expressed in more than 60% of breast tumors, which promotes the growth of estrogen receptor-negative (ER–...
作者:Yuning Liao , Jianyu Cai ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2016, Vol.478 (3), pp.1236-1241
摘要:Abstract(#br)Cardiac hypertrophy, a compensatory response to various stimuli in the heart, independently predicts cardiovascular ailments and related deaths. Increasing evidence indicates ubiquitin-proteasome signaling contributes to cardiac hypertrophy regulation. Here, we ...
作者:Yuning Liao , Hongbiao Huang ...
来源:[J].Biochemical Pharmacology(IF 4.576), 2016, Vol.116, pp.22-38
摘要:Abstract(#br)DNA is the well-known molecular target of current platinum-based anticancer drugs; consequently, their clinical use is severely restricted by their systemic toxicities and drug resistance originating from non-selective DNA damage. Various strategies have been develop...
作者:Yuning Liao , Zhiqiang Guo ...
来源:[J].Oncogenesis, 2018, Vol.7 (9), pp.1461-1484
摘要:Abstract(#br)Estrogen receptor α (ERα) is expressed in ~67% of breast cancers and is critical to their proliferation and progression. The expression of ERα is regarded as a major prognostic marker, making it a meaningful target to treat breast cancer (BCa). However, ...
作者:Yuning Liao , Peiquan Zhang ...
来源:[J].Scientific Reports(IF 2.927), 2015, Vol.5 (1)
摘要:Abstract(#br)Resistance to chemotherapy is a great challenge to improving the survival of patients with diffuse large B-cell lymphoma (DLBCL), especially those with activated B-cell-like DLBCL (ABC-DLBCL). Therefore it is urgent to search for novel agents for the treatment of DLB...
作者:Gary S. Rachelefsky , Yuning Liao , Rab Faruqi
来源:[J].Annals of Allergy, Asthma & Immunology(IF 3.449), 2007, Vol.98 (3), pp.225-238
摘要:Background(#br)Oropharyngeal adverse events associated with inhaled corticosteroid (ICS) use can affect adherence; however, these effects have been studied less extensively than those that occur systemically.(#br)Objective(#br)To calculate the risk of ICS-induced oral candid...

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