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作者:Yuh Morimoto , Tadashi Baba ...
来源:[J].International Journal of Antimicrobial Agents(IF 4.415), 2015, Vol.46 (6), pp.666-673
摘要:Abstract(#br)We previously reported the first ‘reverse antibiotic’ (RA), nybomycin (NYB), which showed a unique antimicrobial activity against Staphylococcus aureus strains. NYB specifically suppressed the growth of quinolone-resistant S. aureus strains but was not effective...
作者:Yuh Morimoto , Tadashi Baba ...
来源:[J].International Journal of Antimicrobial Agents(IF 4.415), 2012, Vol.39 (6), pp.478-485
摘要:Abstract(#br)By screening cultures of soil bacteria, we re-discovered an old antibiotic (nybomycin) as an antibiotic with a novel feature. Nybomycin is active against quinolone-resistant Staphylococcus aureus strains with mutated gyrA genes but not against those with intact ...
作者:Yuh Morimoto , Teruyo Ito
来源:[J].The Journal of Infectious Diseases(IF 5.848), 2009, Vol.200 (5), pp.715-723
摘要:Panton-Valentine leukocidin (PVL) has long been considered a critical toxin in severe Staphylococcus aureus infection. PVL presumably breaches the body's defense system by lysing human polymorphonuclear cells (PMNs). Recently, however, bioactive peptides—phenol-soluble modul...

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