全部文献期刊会议图书|学者科研项目
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作者:Yueting Peng , Zhongyuan Chen ...
来源:[J].Acta Biomaterialia(IF 5.093), 2019, Vol.88, pp.86-101
摘要:Abstract(#br)Tumors are characterized by extracellular matrix (ECM) remodeling and stiffening. The importance of ECM stiffness in cancer is well known. However, the biomechanical behavior of tumor cells and the underlying mechanotransduction pathways remain unclear. Here, we...
作者:Yueting Peng , Li Li ...
来源:[J].BBA - Molecular Basis of Disease(IF 4.91), 2020, Vol.1866 (3)
摘要:Abstract(#br)One of the hallmarks of cancer progression is strong drug resistance during clinical treatments. The tumor microenvironment is closely associated with multidrug resistance, the optimization of tumor microenvironments may have a strong therapeutic effect. In this stud...
作者:Yueting Peng , Yu Chen ...
来源:[J].BBA - Molecular Cell Research(IF 4.808), 2018, Vol.1865 (1), pp.172-185
摘要:Abstract(#br)Tumor cell can be significantly influenced by various chemical groups of the extracellular matrix proteins. However, the underlying molecular mechanisms involved in the interaction between cancer cells and functional groups in the extracellular matrix remain unk...
作者:Yueting Peng , Hong Yang ...
来源:[J].BBA - Molecular Cell Research(IF 4.808), 2017, Vol.1864 (1), pp.12-22
摘要:Abstract(#br)Tumor cells translocating to distant sites are subjected to hemodynamic shear forces during their passage in the blood vessels. Low shear stress (LSS) plays a critical role in the regulation of various aspects of tumor cells functions, including motility and adhesion...
作者:Yueting Peng , Kai Tang ...
来源:[J].BBA - Molecular Basis of Disease(IF 4.91), 2018, Vol.1864 (7), pp.2395-2408
摘要:Abstract(#br)An acidic extracellular pH (pH e ) in the tumor microenvironment has been suggested to facilitate tumor growth and metastasis. However, the molecular mechanisms by which tumor cells sense acidic signal to induce a transition to an aggressive phenotype remain elu...

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