全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Ssu-Yao Hu , Wen-Te Hsiao , Yuan-Soon HO
来源:[J].Journal of Biomedical Science(IF 2.458), 2003, Vol.10 (2), pp.199-207Springer
摘要:Abstract(#br)We cultured a P19 mouse teratocarcinoma cell line and induced its neuronal differentiation to study the function of ionotropic glutamate receptors (GluRs) in early neuronal development. Immunocytochemical studies showed 85% neuronal population at 5 days in vitro...
作者:... Chien-Hsi Chang , How Tseng , Yuan-Soon Ho
来源:[J].Journal of Cancer Research and Therapeutics(IF 0.761), 2012, Vol.8 (4), pp.532-536DOAJ
摘要:Context: The compound 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) has been isolated from several different plant species, including Petroselinum sativum. Our recent study found that apiole is a chemical derivative of 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-...
作者:... Chih-Hsiung Wu , Wendy-Hwang Verslues , Yuan-Soon Ho
来源:[J].Human Pathology(IF 2.843), 2018Elsevier
摘要:Summary(#br)The transcription factor GATA3 plays a significant role in mammary gland development and differentiation. We analyzed expression of GATA3 in breast cancer (BC) cell lines and clinical specimens from BC patients in Taiwan. Semi-quantitative reverse transcriptase (...
作者:Yuan-Soon Ho , Yi-You Huang ...
来源:[J].European Journal of Pharmaceutics and Biopharmaceutics(IF 3.826), 2018, Vol.123, pp.9-19Elsevier
摘要:Abstract(#br)In the present study, we attempted to develop a lecithin-stabilized micellar drug delivery system (L sb MDDs) for loading docetaxel (DTX) to enhance its therapeutic efficacy and minimize systemic toxicity. A novel DTX-loaded L sb MDDs was optimally prepared by a...
作者:... Jacqueline Whang-Peng , Teng-Nan Lin , Yuan-Soon Ho
来源:[J].Journal of Food and Drug Analysis(IF 0.333), 2018, Vol.26 (1), pp.221-231Elsevier
摘要:Abstract(#br)Human triple-negative breast cancer (TNBC) is the most aggressive and poorly understood subclass of breast cancer. Glucose transporters (GLUTs) are required for glucose uptake in malignant cancer cells and are ideal targets for cancer therapy. To determine wheth...
作者:Yuan-Soon Ho , Tsu-Yi Chao
来源:[J].Experimental Cell Research(IF 3.557), 2018Elsevier
摘要:Abstract(#br)Failure to eradicate hematologic cancer stem cells (hCSCs) associated with resistance to tyrosine kinase inhibitors such as imatinib mesylate (IM) in chronic myeloid leukemia (CML) patients is a clinical challenge that highlights the need for discovering and dev...
作者:... Chih-Hsiung Wu , Wen-Sen Lee , Yuan-Soon Ho
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2012, Vol.134 (3), pp.989-1004Springer
摘要:Abstract(#br)The extracellular matrix (ECM) plays a critical role in the development and invasion of primary breast tumors. Lysyl oxidase (LOX), which is an ECM remodeling enzyme, appears to play roles in promoting cancer cell motility and invasion. To ascertain whether LOX ...
作者:Shih-Hsin Tu , Li-Ching Chen , Yuan-Soon Ho
来源:[J].Journal of Food and Drug Analysis(IF 0.333), 2016Elsevier
摘要:Abstract(#br)The purpose of this review is to update and discuss key findings from in vitro and in vivo studies on apple and its biocompounds, with a special focus on its anticancer role. Several studies have proposed that apple and its extracts exhibit a variety of biological fu...
作者:... Li-Ching Chen , Yuan-Soon Ho , Ying-Jan Wang
来源:[J].Toxicology(IF 4.017), 2008, Vol.246 (2), pp.148-157Elsevier
摘要:Abstract(#br)The increased expression and cross-linking activity of tissue transglutaminase (tTG) have been demonstrated in acute liver injury and fibrosis. We focused on the molecular mechanisms that contribute to ethanol-induced tTG expression and investigated the efficacy...
作者:Yuan-Soon Ho , Chuan-Yu Lin
来源:[J].Toxicology(IF 4.017), 2005, Vol.220 (2), pp.81-89Elsevier
摘要:Abstract(#br)Arecoline, the main areca alkaloid in betel quid (BQ), is reported to have cytotoxic, genotoxic, and mutagenic effects in various cells. It shows strong correlation to the incidence of oral submucous fibrosis, leukoplakia, and oral cancer. To clarify the role of...

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