全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Yoshiyuki Mizushina , Xianai Xu ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2019, Vol.92 (3), pp.283-290DOAJ
摘要:As described previously (H. Togashi et al. Biochem Pharmacol. 1998;56:583–590), the irradiated products of provitamin D2 (ergosterol) inhibit the activities of eukaryotic DNA polymerases. In this report, therefore, we investigated whether vitamin D and its related compounds ...
作者:Yoshiyuki Mizushina , Jun Maeda ...
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2011, Vol.12 (2), pp.1115DOAJ
摘要:Previously, we reported that vitamin K3 (VK3), but not VK1 or VK2 (=MK-4), inhibits the activity of human DNA polymerase γ (pol γ). In this study, we chemically synthesized three intermediate compounds between VK2 and VK3, namely MK-3, MK-2 and MK-1, and investigated the inh...
作者:Yoshiyuki Mizushina , Kenji Yoshida ...
来源:[J].Radiation Oncology(IF 2.107), 2016, Vol.11 (1)Springer
摘要:Abstract(#br) Background(#br)In our previous study, monogalactosyl diacylglycerol (MGDG) purified from spinach was found to have cytotoxic effects in human cancer cell lines. This study further assessed whether MGDG can enhance the cytotoxic effects of radiation in human pan...
作者:... Naoya Fuse , Yoshiyuki Mizushina , Hitoshi Ashida
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2015, Vol.16 (7), pp.16288-16299DOAJ
摘要:Tea catechins promote glucose uptake in skeletal muscle cells. In this study, we investigated whether the addition of an acyl group to the C-3 position of catechins to generate 3-O-acyl-catechins promoted glucose uptake in L6 myotubes. 3-O-Myristoyl-(−)-epicatechin (EC-C14) ...
作者:Yoshiyuki Mizushina , Hirohisa Motoshima ...
来源:[J].Marine Drugs(IF 3.978), 2009, Vol.7 (4), pp.624DOAJ
摘要:We isolated a pol inhibitor from the cultured mycelia extract of a fungal strain isolated from natural salt from a sea salt pan in Australia, which was identified as 3-O-methylfunicone by spectroscopic analyses. This compound selectively inhibited the activities of mammalian...
作者:... Naoko Yoshida , Kyoko Shibata , Yoshiyuki Mizushina
来源:[J].Nutrients(IF 2.072), 2010, Vol.2 (1), pp.49DOAJ
摘要:Regiospecific distributions of fatty acids (FA) of triacylglycerols (TAG) and phospholipids (PL) isolated from five cultivars of adzuki beans (Vigna angularis) were investigated. The lipids comprised mainly PL (72.2–73.4 wt-%) and TAG (20.6–21.9 wt-%), whilst other component...
作者:Yoshiyuki Mizushina , Xianai Xu ...
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2003, Vol.92 (3), pp.283-290Elsevier
摘要:Abstract(#br)As described previously (H. Togashi et al. Biochem Pharmacol. 1998;56:583–590), the irradiated products of provitamin D 2 (ergosterol) inhibit the activities of eukaryotic DNA polymerases. In this report, therefore, we investigated whether vitamin D and its rela...
作者:Yoshiyuki Mizushina , Daisuke Manita ...
来源:[J].Molecules(IF 2.428), 2008, Vol.14 (1), pp.102DOAJ
摘要:We previously isolated a novel natural product, designated kohamaic acid A (KA-A, compound 1), as an inhibitor of the first cleavage of fertilized sea urchin eggs, and found that this compound could selectively inhibit the activities of mammalian DNA polymerases (pols). In t...
作者:Yoshiyuki Mizushina , Hiromi Yoshida , Yuko Yonezawa
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2007, Vol.8 (12), pp.1206-1224DOAJ
摘要:DNA topoisomerases (topos) and DNA polymerases (pols) are involved in manyaspects of DNA metabolism such as replication reactions. We found that long chainunsaturated fatty acids such as polyunsaturated fatty acids (PUFA) (i.e., eicosapentaenoicacid (EPA) and docosahexaenoic...
作者:Yoshiyuki Mizushina , Kyoko Shibata ...
来源:[J].Nutrients(IF 2.072), 2010, Vol.2 (1), pp.49-59DOAJ
摘要:Regiospecific distributions of fatty acids (FA) of triacylglycerols (TAG) and phospholipids (PL) isolated from five cultivars of adzuki beans (Vigna angularis) were investigated. The lipids comprised mainly PL (72.2–73.4 wt-%) and TAG (20.6–21.9 wt-%), whilst other component...

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