全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Motoko Tachihara , Hiroshi Kamiryo , Yoshihiro Nishimura
来源:[J].Respiratory Research(IF 3.642), 2016, Vol.17 (1)Springer
摘要:Abstract(#br) Background(#br)Sphingosine-1-phosphate (S1P) is a bioactive phospholipid that acts as a signal transducer by binding to S1P receptors (S1PR) 1 to 5. The S1P/S1PRs pathway has been associated with remodeling and allergic inflammation in asthma, but the expressio...
作者:... Eri Shimada , Yoshihiro Nishimura , Hiroshi Sakurai
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (5)DOAJ
摘要:Extracellular signal-regulated kinase (ERK) signalling plays a central role in various biological processes, including cell migration, but it remains unknown what factors directly regulate the strength and duration of ERK activation. We found that, among the B56 family of pr...
作者:... Kazuyuki Kobayashi , Takeshi Usui , Yoshihiro Nishimura
来源:[J].OncoTargets and Therapy(IF 2.073), 2018, Vol.2018 (default), pp.1595-1599Dove
摘要:Hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) syndrome is an autosomal dominant condition caused by mutations of the gene encoding the dual zinc-finger transcription factor, GATA3. A previous study identified some patients with GATA3 gene variants and b...
作者:... Hajime Karasuyama , Masaru Yoshida , Yoshihiro Nishimura
来源:[J].Respiratory Research(IF 3.642), 2011, Vol.12 (1), pp.1-10Springer
摘要:Abstract(#br) Background(#br)There have been few reports on the role of Fc receptors (FcRs) and immunoglobulin G (IgG) in asthma. The purpose of this study is to clarify the role of inhibitory FcRs and antigen presenting cells (APCs) in pathogenesis of asthma and to evaluate...
作者:Yoshihiro Nishimura , Hitoshi Yamagata
来源:[J].Japanese Journal of Radiology(IF 0.73), 2015, Vol.33 (2), pp.76-83Springer
摘要:Abstract(#br) Purpose(#br)To compare primarily viewing axial images (Axial mode) versus coronal reconstruction images (Coronal mode) in computer-aided detection (CAD) of lung nodules on multidetector computed tomography (CT) in terms of detection performance and reading time...
作者:Yoshihiro Nishimura , Hiroyuki Tanaka ...
来源:[J].Acta Histochemica(IF 1.608), 2014, Vol.116 (5), pp.702-707Elsevier
摘要:Abstract(#br)Chicken d -serine dehydratase (DSD) degrades d -serine to pyruvate and ammonia. The enzyme requires both pyridoxal 5′-phosphate and Zn 2+ for its activity. d -Serine is a physiological coagonist that regulates the activity of the N -methyl- d -aspartate receptor...
作者:... Hirohiko Akiyama , Yoshihiro Nishimura , Koichi Kobayashi
来源:[J].The Journal of Thoracic and Cardiovascular Surgery(IF 3.526), 2003, Vol.127 (4), pp.1107-1112Elsevier
摘要:Abstract(#br)Objective(#br)The long-term results of the surgical treatment for patients with pulmonary metastases from uterine malignancies were clarified.(#br)Methods(#br)A total of 133 patients who underwent pulmonary metastasectomy for uterine malignancies were enrolled i...
作者:... Motoko Tachihara , Yoshikazu Kotani , Yoshihiro Nishimura
来源:[J].Cancer Letters(IF 4.258), 2014, Vol.343 (1), pp.74-79Elsevier
摘要:Abstract(#br)The purpose is to examine the synergistic effect of pemetrexed (PEM) and amrubicin (AMR) on the proliferation of lung cancer cell lines. In vitro , dose-dependent synergistic effects of concurrent PEM and AMRol, which is an active metabolite of AMR were observed in A...
作者:... Naoki Sugihara , Yoshihiro Nishimura , Kazuro Sugimura
来源:[J].European Journal of Radiology(IF 2.512), 2016, Vol.85 (2), pp.352-359Elsevier
摘要:Abstract(#br)Purpose(#br)To evaluate the utility of three-dimensional (3D) lung motion on inspiratory and expiratory CT for pulmonary functional loss in smoking-related COPD in comparison with lung destruction and air trapping assessments.(#br)Method and materials(#br)Forty-...
作者:... Tadashi Ishida , Yoshihiro Nishimura , Yasushi Yatabe
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2015, Vol.10 (11), pp.1553-1559Elsevier
摘要:Introduction(#br)Epidermal growth factor receptor (EGFR) mutation T790M accounts for approximately half of acquired resistances to EGFR-tyrosine kinase inhibitor (TKI). Because T790M is mediated by TKI exposure, its penetration and “on–off” may affect T790M status.(#br)...

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