全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Ymera Pignochino , Federica Capozzi ...
来源:[J].Molecular Cancer(IF 5.134), 2017, Vol.16 (1)Springer
摘要:Enhancing the antitumor activity of the DNA-damaging drugs is an attractive strategy to improve current treatment options. Trabectedin is an isoquinoline alkylating agent with a peculiar mechanism of action. It binds to minor groove of DNA inducing single- and double-strand-break...
作者:Ymera Pignochino , Carmine Dell’Aglio ...
来源:[J].BMC Cancer(IF 3.333), 2015, Vol.15 (1)Springer
摘要:Abstract(#br) Background(#br)Malignant Pleural Mesothelioma (MPM) is an aggressive tumor arising from mesothelial cells lining the pleural cavities characterized by resistance to standard therapies. Most of the molecular steps responsible for pleural transformation remain un...
作者:Ymera Pignochino , Giuliana Cavalloni ...
来源:[J].BMC Cancer(IF 3.333), 2011, Vol.11 (1)Springer
摘要:Abstract(#br) Background(#br)Activating mutations of the epidermal growth factor receptor ( EGFR ) confer sensitivity to the tyrosine kinase inhibitors (TKi), gefitinib and erlotinib. We analysed EGFR expression, EGFR mutation status and gene expression profiles of prostate cance...
作者:Ymera Pignochino , Silvia Benvenuti ...
来源:[J].International Journal of Nanomedicine(IF 3.463), 2019, Vol.2019 (default), pp.773-785Dove
摘要:Purpose: Malignant Pleural Mesothelioma (MPM) is an aggressive tumour characterized by poor prognosis. Its incidence is steadily increasing due to widespread asbestos exposure. There is still no effective therapy for MPM. Pemetrexed (Pe) is one of the few chemotherapeutic agents ...
作者:Ymera Pignochino , Dario Sangiolo ...
来源:[J].Lancet Oncology(IF 25.117), 2015, Vol.16 (1), pp.98-107Elsevier
摘要:Summary(#br)Background(#br)Results of previous study showed promising but short-lived activity of sorafenib in the treatment of patients with unresectable advanced and metastatic osteosarcoma. This treatment failure has been attributed to the mTOR pathway and might therefore...
作者:Ymera Pignochino , Michele Zorzetto ...
来源:[J].Translational Oncology(IF 3.393), 2014, Vol.7 (5), pp.650-655Elsevier
摘要:Abstract(#br)Idiopathic pulmonary fibrosis (IPF) is defined as a specific form of chronic, progressive fibrosing interstitial pneumonia of unknown cause. The most recent hypotheses on IPF pathogenesis suggest a central role of epithelial cell damage, followed by a dysregulat...
作者:Ymera Pignochino , Giovanni Grignani ...
来源:[J].Expert Opinion on Biological Therapy(IF 3.345), 2015, Vol.15 (4), pp.517-528Taylor & Francis
摘要:Introduction: (#br) Conventional treatments reached an unsatisfactory therapeutic plateau in the treatment of advanced unresectable bone and soft tissue sarcomas that remain an unsolved medical need. Several evidences support the concept that adoptive immunotherapy may effec...
作者:Ymera Pignochino , Laura Berta ...
来源:[J].Experimental Hematology(IF 2.907), 2005, Vol.33 (11), pp.1371-1387Elsevier
摘要:Objective(#br)Cord blood CD34 + cells are more uncommitted than their adult counterparts as they can be more easily maintained and expanded in vitro and transduced with lentiviral vectors. The aim of this study was to evaluate whether pretreatment with high-energy shock wave...
作者:Ymera Pignochino , Wanda Piacibello
来源:[J].Biology of Blood and Marrow Transplantation(IF 3.94), 2005, Vol.12 (1), pp.68-74Elsevier
摘要:Abstract(#br)Tumor cell contamination might induce relapse after autologous transplantation in breast cancer patients. We used an ex vivo purging strategy to decrease the number of contaminating breast tumor cells in leukaphereses without altering the engraftment potential o...

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