全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Qinghua Jiang , Li Xu , Yadong Wang
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (1)Springer
摘要:The development of single-cell RNA sequencing has enabled profound discoveries in biology, ranging from the dissection of the composition of complex tissues to the identification of novel cell types and dynamics in some specialized cellular environments. However, the large-scale ...
作者:... Weiwei Hui , Yadong Wang , Xuequn Shang
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (16)Springer
摘要:The Gene Ontology (GO) is a community-based bioinformatics resource that employs ontologies to represent biological knowledge and describes information about gene and gene product function. GO includes three independent categories: molecular function, biological process and cellu...
作者:... Liang Cheng , Yadong Wang , Jin Chen
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer
摘要:Identifying the genes associated to human diseases is crucial for disease diagnosis and drug design. Computational approaches, esp. the network-based approaches, have been recently developed to identify disease-related genes effectively from the existing biomedical networks. Mean...
作者:Yadong Wang , Clark Wells ...
来源:[J].Human Genetics(IF 4.633), 2017, Vol.136 (9), pp.1279-1289Springer
摘要:While synonymous single-nucleotide variants (sSNVs) have largely been unstudied, since they do not alter protein sequence, mounting evidence suggests that they may affect RNA conformation, splicing, and the stability of nascent-mRNAs to promote various diseases. Accurately priori...
作者:... Peigang Xu , Yadong Wang , Liang Cheng
来源:[J].Journal of Biomedical Semantics, 2017, Vol.8 (1)Springer
摘要:Functional similarity between molecules results in similar phenotypes, such as diseases. Therefore, it is an effective way to reveal the function of molecules based on their induced diseases. However, the lack of a tool for obtaining the similarity score of pair-wise disease sets...
作者:... Zhen Wang , Bo Liu , Yadong Wang
来源:[J].BMC Bioinformatics(IF 3.024), 2019, Vol.20 (S8), pp.1-7DOAJ
摘要:Abstract Background Numerous essential algorithms and methods, including entropy-based quantitative methods, have been developed to analyze complex DNA sequences since the last decade. Exons and introns are the most notable components of DNA and their identification and predictio...
作者:Yang Bai , Shufan Ji , Yadong Wang
来源:[J].BMC Genomics(IF 4.397), 2015, Vol.16 (S2)Springer
摘要:Abstract(#br) Background(#br)The emergence of next-generation RNA sequencing (RNA-Seq) provides tremendous opportunities for researchers to analyze alternative splicing on a genome-wide scale. However, accurate detection of intron retention (IR) events from RNA-Seq data has remai...
作者:... Yangyang Hao , Yadong Wang , Yunlong Liu
来源:[J].BMC Genomics(IF 4.397), 2016, Vol.17 (7)Springer
摘要:Abstract(#br) Background(#br)Ion Torrent and Ion Proton are semiconductor-based sequencing technologies that feature rapid sequencing speed and low upfront and operating costs, thanks to the avoidance of modified nucleotides and optical measurements. Despite of these advantages, ...
作者:... Yucui Dong , Guohui Zhou , Yadong Wang
来源:[J].BMC Bioinformatics(IF 3.024), 2015, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)Because of the short read length of high throughput sequencing data, assembly errors are introduced in genome assembly, which may have adverse impact to the downstream data analysis. Several tools have been developed to eliminate these errors by eithe...

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