全部文献期刊会议图书|学者科研项目
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作者:Xuesi Chen , Shujie Liu
来源:[J].Chemical Research in Chinese Universities(IF 0.735), 2017, Vol.33 (3), pp.499-506
摘要:The bioglass particles/poly(lactide-co-glycolide)(BG/PLGA) scaffold has been extensively explored for biomedical applications due to its excellent advantages of mechanical property and controllable degradation rate. In our previous studies, the BG nanoparticle surface-grafted wit...
作者:... Zhaohui Tang , Xueqi Fu , Xuesi Chen
来源:[J].Science China Materials, 2017, Vol.60 (10), pp.995-1007
摘要:Osteosarcoma is a high-class malignant bone cancer with a less than 20% five-year survival rate due to its early metastasis potential. There is an urgent need to develop a versatile and innoxious drug to treat metastatic osteosarcoma. Curcumin (Cur) has shown its potential f...
作者:... Xinchao Bian , Gao Li , Xuesi Chen
来源:[J].Polymer Testing(IF 1.646), 2020, Vol.81
摘要:Abstract(#br)The thermogravimetric analysis (TGA) was used to evaluate the polylactide (PLA) content in PLA/poly(butylene adipate- co -terephthalate) (PLA/PBAT) blends. The TGA curves of PLA/PBAT blends containing magnesium oxide (MgO) can clearly show two-step weight loss p...
作者:... Lili Ma , Zhaohui Tang , Xuesi Chen
来源:[J].Biomaterials(IF 7.604), 2020, Vol.232
摘要:Abstract(#br)Tumor is known as “a wound that does not heal”. Tumor-promoting inflammation plays a crucial role in carcinogenesis, tumor progression, tumor metastasis, as well as chemotherapy resistance. Therefore, reducing tumor-promoting inflammation may be a key aspect in ...
作者:... Zhongming Li , Jianxun Ding , Xuesi Chen
来源:[J].Biomaterials(IF 7.604), 2020, Vol.230
摘要:Abstract(#br)Tissue engineering is a promising strategy for the repair of large-scale bone defects, in which scaffolds and growth factors are two critical issues influencing the efficacy of bone regeneration. Unfortunately, the broad application of growth factors is limited by th...
作者:... Ziling Liu , Kazuo Sakurai , Xuesi Chen
来源:[J].Acta Biomaterialia(IF 5.093), 2019, Vol.92, pp.229-240
摘要:Abstract(#br)Effective systemic therapy is highly desired for the treatment of hepatocellular carcinoma (HCC). In this study, a combination of nanoparticles of poly(L-glutamic acid)- graft -methoxy poly(ethylene glycol)/combretastatin A4 sodium salt (CA4-NPs) plus sorafenib ...
作者:... Shu Sheng , Huayu Tian , Xuesi Chen
来源:[J].Biomaterials(IF 7.604), 2019, Vol.216
摘要:Abstract(#br)Targeted activation or enhancement is an attractive strategy in the design of nano-theranostics. However, the responsiveness of the nanoagents is restricted by the limited levels of intra-tumor stimuli. Herein, we constructed a positive feedback nanoamplifier by...
作者:... Gao Xiao , Jianxun Ding , Xuesi Chen
来源:[J].Acta Biomaterialia(IF 5.093), 2018
摘要:Abstract(#br)Topical chemotherapy with complementary drugs is one of the most promising strategies to achieve an effective antitumor activity. Herein, a synergistic strategy for hepatoma therapy by the combination of tumor microenvironment-sensitive polymer−doxorubicin (DOX)...
作者:... Chunsheng Xiao , Xiuli Zhuang , Xuesi Chen
来源:[J].European Polymer Journal(IF 2.562), 2017, Vol.88, pp.67-74
摘要:Abstract(#br)Nowadays, injectable electroactive hydrogels have received much attention in biomedical field. In this article, an electroactive copolymer was successfully synthesized by chemical coupling of tetraaniline (TA) onto the chain end of Pluronic ® F127. The structure...
作者:... Nasha Qiu , Xuesi Chen , Youqing Shen
来源:[J].Advanced Drug Delivery Reviews(IF 12.888), 2017
摘要:Abstract(#br)Gene therapy represents a promising cancer treatment featuring high efficacy and limited side effects, but it is stymied by a lack of safe and efficient gene-delivery vectors. Cationic polymers and lipid-based nonviral gene vectors have many advantages and have been ...

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