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作者:... Ying Li , Xizhen Ge , Pingfang Tian
来源:[J].Crop Protection(IF 1.303), 2019, Vol.116, pp.92-100
摘要:Abstract(#br)The brown rot disease caused by fungus Monilinia fructicola severely reduces the yield of peach and other stone fruits. Earlier, we found that berberine (BBR), one of isoquinoline alkaloids, strongly halts the growth of M . fructicola . However, the underlying mechan...
作者:... Qinghui Pei , Xizhen Ge , Pingfang Tian
来源:[J].Crop Protection(IF 1.303), 2016
摘要:Abstract(#br)Berberine (BBR) is a traditional antidiarrheal compound with excellent safety profiles. Our previous study reported that BBR strongly inhibited brown rot pathogen Monilinia fructicola . In this study we assess its potential commercial performance. We found that ...
作者:... Ying Li , Xizhen Ge , Pingfang Tian
来源:[J].Biotechnology Letters(IF 1.853), 2015, Vol.37 (3), pp.717-724
摘要:Abstract(#br)In Klebsiella pneumoniae , aldehyde dehydrogenases (ALDH) convert 3-hydroxypropionaldehyde (3-HPA) into 3-hydroxypropionic acid (3-HP). Although ALDHs can increase the production of 3-HP in K. pneumoniae , the substrate specificity of ALDH homologues from other ...
作者:... Xi Wang , Xizhen Ge , Pingfang Tian
来源:[J].Scientific Reports(IF 2.927), 2016, Vol.6 (1), pp.622-626
摘要:Abstract(#br)3-Hydroxypropionic acid (3-HP) is an important platform chemical proposed by the United States Department of Energy. 3-HP can be converted to a series of bulk chemicals. Biological production of 3-HP has made great progress in recent years. However, low yield of 3-HP...
作者:... Mingyue Su , Xizhen Ge , Pingfang Tian
来源:[J].Biotechnology Letters(IF 1.853), 2013, Vol.35 (10), pp.1609-1615
摘要:Abstract(#br)In Klebsiella pneumoniae , 3-hydroxypropaldehyde is converted to 3-hydroxypropionic acid (3-HP) by aldehyde dehydrogenase (ALDH) with NAD + as a cofactor. Although ALDH overexpression stimulates the formation of 3-HP, it ceases to accumulate when NAD + is exhausted. ...
作者:... Xi Wang , Xizhen Ge , Pingfang Tian
来源:[J].Indian Journal of Microbiology(IF 0.457), 2012, Vol.52 (3), pp.478-483
摘要:Abstract(#br)3-Hydroxypropionic acid (3-HP) is a commercially valuable platform compound. Klebsiella pneumoniae has been concerned as an appropriate host for 3-HP production because of its robust capacity to metabolize glycerol. Glycerol conversion to 3-HP in K. pneumoniae compri...
作者:Ying Li , Xizhen Ge , Pingfang Tian
来源:[J].Indian Journal of Microbiology(IF 0.457), 2013, Vol.53 (4), pp.418-424
摘要:Abstract(#br)Biosynthesis of 3-hydroxypropionic acid (3-HP) typically involves two sequential reactions catalyzed by glycerol dehydratase (DhaB) and aldehyde dehydrogenase (AldH). Although plasmid-dependent over-expression of the two enzymes is common, systematic investigation of...
作者:... Zengye Han , Xizhen Ge , Pingfang Tian
来源:[J].Current Microbiology(IF 1.52), 2014, Vol.69 (4), pp.451-456
摘要:Abstract(#br)Pyrroloquinoline quinone (PQQ) is a versatile quinone cofactor participating in numerous biological processes. Klebsiella pneumoniae can naturally synthesize PQQ for harboring intact PQQ synthesis genes. Previous metabolic engineering of K . pneumoniae failed to...
作者:Chunqi Yan , Xizhen Ge , Pingfang Tian
来源:[J].Fruits(IF 0.776), 2012, Vol.67 (4), pp.277-284
摘要:Introduction .Peach brown rot caused by the fungus Monilinia fructicola is a major disease leadingto considerable economic loss during storage. Our previous studyuncovered the striking inhibition of the natural alkaloid berberineagainst M. fructicola . Materials and methods ...

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