全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Yue-e Teng , Xiujuan Qu , Yunpeng Liu
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Although the efficacy of tamoxifen (TAM) for breast cancer has been attributed to inducing cell cycle arrest and apoptosis by inhibiting estrogen receptor (ER) signaling, recent evidence indicates that TAM also possesses ER-independent antitumor activity through an unclear mechan...
作者:Xiujuan Qu , Ling Xu ...
来源:[J].Molecular Cancer(IF 5.134), 2017, Vol.16 (1)Springer
摘要:The insulin-like growth factor-I (IGF-I) signaling induces epithelial to mesenchymal transition (EMT) program and contributes to metastasis and drug resistance in several subtypes of tumors. In preclinical studies, targeting of the insulin-like growth factor-I receptor (IGF-IR) s...
作者:... Kezuo Hou , Xiujuan Qu , Yunpeng Liu
来源:[J].Molecular and Cellular Biochemistry(IF 2.329), 2017, Vol.436 (1-2), pp.29-38Springer
摘要:The ATR/checkpoint kinase 1 (Chk1) pathway plays an essential role in modulating the DNA damage response and homologous recombination. Particularly, Chk1 phosphorylation is related to cancer prognosis and therapeutic resistance. Some receptor tyrosine kinases participate in ...
作者:... Hang Su , Xiujuan Qu , Yunpeng Liu
来源:[J].BMC Cancer(IF 3.333), 2019, Vol.19 (1), pp.1-6DOAJ
摘要:Abstract Background The epidermal growth factor receptor (EGFR)-mutated advanced non-small-cell lung cancer has been successfully treated with tyrosine kinase inhibitors (TKIs). Acquired resistance becomes a tough issue when patients fail to respond to the third-generation TKI os...
作者:... Xianghong Yang , Xiujuan Qu , Yunpeng Liu
来源:[J].BMC Cancer(IF 3.333), 2018, Vol.18 (1), pp.1-14DOAJ
摘要:Abstract Background MicroRNAs can be used in the prognosis of malignancies; however, their regulatory mechanisms are unknown, especially in pancreatic ductal adenocarcinoma (PDAC). Methods In 120 PDAC specimens, miRNA levels were assessed by quantitative real time polymerase...

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