全部文献期刊会议图书|学者科研项目
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作者:... Xuemei Tang , Xingran Xu , Dacheng Yang
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2019, Vol.27 (1), pp.175-187
摘要:Abstract(#br)Based on the advantages of azole molecules and fluoroquinolone drugs, we designed and synthesized 34 clinafloxacin-azole conjugates using fragment-based drug design and drug combination principles. The in vitro activities of the synthesized conjugates against My...
作者:Xingran Xu , Qingchan Zhang ...
来源:[J].Virus Research(IF 2.745), 2006, Vol.122 (1), pp.164-170
摘要:Abstract(#br)In present study, we report the first complete genomic sequence of pig bovine viral diarrhea (BVD) virus, that of strain ZM-95, which is 12,220 nucleotides long and contains short 5′ and 3′ non-coding regions and one open reading frame encoding a large polyprote...
作者:Xingran Xu , Huancheng Guo ...
来源:[J].Antiviral Research(IF 3.925), 2007, Vol.78 (3), pp.188-193
摘要:Abstract(#br)Classical swine fever (CSF) is a highly contagious disease of pigs, which causes important economic losses worldwide. In the present study, the specific effect of RNA interference on the replication of CSF virus (CSFV) was explored. Three species of small interf...
作者:Ailing Fu , Rumei Zhou , Xingran Xu
来源:[J].Neural Regeneration Research(IF 0.144), 2014, Vol.9 (8), pp.864-871
摘要:The thyroid hormones, triiodothyronine and thyroxine, play important roles in cognitive function during the mammalian lifespan. However, thyroid hormones have not yet been used as a therapeutic agent for normal age-related cognitive deficits. In this study, CD-1 mice (aged 2...
作者:Xingran Xu , Yuqi Huang
来源:[J].Journal of Drug Targeting(IF 2.768), 2011, Vol.19 (8), pp.632-636
摘要:Targeted delivery of proteins into the hippocampus has not yet been achieved. Here, we show that systemic administration of the β-galactosidase, fused to a 43-amino-acid peptide derived from rabies virus glycoprotein (RVG), results in targeted delivery of the fusion protein ...
作者:Xingran Xu , Lei Chen ...
来源:[J].Journal of Physics B: Atomic, Molecular and Optical Physics(IF 2.031), 2019, Vol.52 (2)
摘要:By adopting a mean-field Gross–Pitaevskii description of spinor polariton Bose–Einstein condensates under nonresonant pumping, we investigate the static and dynamical properties of dark–bright (DB) solitons. We derive the equation of motion for the center of mass of the...
作者:... Feiyan Gao , Xingran Xu , Zhangbao Chen
来源:[J].PLOS ONE(IF 3.73), 2013, Vol.8 (3)
摘要:There is no data up to now to show that peptide can deliver plasmid into brain as a single-component transfer vector. Here we show that a novel peptide, RDP (consisted of 39 amino acids), can be exploited as an efficient plasmid vector for brain-targeting delivery. The plasm...

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