全部文献期刊会议图书|学者科研项目
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作者:Xing Dai , Chengling Pan
来源:[J].Russian Journal of Physical Chemistry A(IF 0.386), 2017, Vol.91 (12), pp.2425-2430
摘要:First-principles calculations are performed to investigate the crystal and electronic structures of BiOF crystal and its oxygen vacancy BiO7/8F. By analyzing the energy band structures, the total density of states and the partial densities of states, it is found that t...
作者:Xing Dai , Hong Liu ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2020, Vol.30 (7)
摘要:Abstract(#br)In a lead optimization effort towards NS5B NNI inhibitors, two multi-step parallel libraries were designed and successfully synthesized. Through this effort we discovered compound 9B , which achieved rigorous and delicate balance of inhibition across the common genot...
作者:... Enrico Gratton , Qing Nie , Xing Dai
来源:[J].Cell Reports, 2020, Vol.30 (11), pp.3932-3947.e6
摘要:Summary(#br)Our knowledge of transcriptional heterogeneities in epithelial stem and progenitor cell compartments is limited. Epidermal basal cells sustain cutaneous tissue maintenance and drive wound healing. Previous studies have probed basal cell heterogeneity in stem and ...
作者:Xing Dai , Mingyao Liu ...
来源:[J].Journal of Investigative Dermatology(IF 6.193), 2019
摘要:It is known that LGR4 plays an important role in hair follicle (HF) development, but the impact of LGR4 on the hair cycle is still unclear. In this study, we have found that K14 -Cre–mediated skin epithelia–specific deletion of Lgr4 results in delayed anagen entry during the...
作者:Xing Dai , Hong Liu ...
来源:[J].Tetrahedron Letters(IF 2.397), 2017
摘要:Abstract(#br)We report a general approach for the synthesis of 5,6-dihydroindolo-naphthyridine ring system via an intramolecular cyclization of the indole NH to an alkene moiety as the key step.
作者:Xing Dai , Shuwen He ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2019, Vol.29 (24)
摘要:Abstract(#br)Hepatitis C virus (HCV) NS5B polymerase is a prime target for the development of direct-acting antiviral drugs for the treatment of chronic HCV infection. Several novel and potent HCV NS5B non-nucleoside inhibitors with unique tetracyclic bezonfuran-based structures ...
作者:... Xuezhe Han , Xijing He , Xing Dai
来源:[J].Archives of Medical Research(IF 2.079), 2019, Vol.50 (1), pp.47-57
摘要:Background and Aims(#br)Osteosarcoma is one of the most pernicious primary bone tumor characterized by high malignancy and metastasis, however its pathogenesis remain largely unknown. Our previous study showed elevated expression of adrenomedullin (ADM) is correlated with prognos...
作者:Xing Dai , Hong Deng ...
来源:[J].Applied Catalysis B: Environmental(IF 5.825), 2019, Vol.254, pp.47-54
摘要:Abstract(#br)Uranium enrichment is perhaps the most critical chemical process throughout the nuclear fuel cycle including uranium mining, uranium extraction from seawater, used fuel reprocessing and disposal, and environmental contamination remediation. New uranium extraction tec...
作者:Xing Dai , Andrew Stamford ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2015, Vol.25 (22), pp.5291-5294
摘要:Abstract(#br)The design and synthesis of two conformationally restricted oxazabicyclo octane derivatives as GRP119 agonists is described. Derivatives of scaffold C , with syn configuration, have the best overall profiles with respect to solubility and in vivo efficacy. Compound 2...

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