全部文献期刊会议图书|学者科研项目
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作者:Xiaobing Ye , Gang Liu ...
来源:[J].Atherosclerosis(IF 3.706), 2018, Vol.270, pp.68-75
摘要:Abstract(#br)Background and aims(#br)Chronic intermittent hypoxia (CIH) exposure causes atherosclerosis, although the underlying mechanisms are poorly understood. This study defines the role of endothelial intrinsic NF-κB signaling in the atherogenic response to CIH.(#br)Met...
作者:Xiaobing Ye , Hong Liu ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (6)
摘要:Specificity protein (Sp) 1 mediates the transcription of a large number of constitutive genes encoding physiological mediators. NF-κB mediates the expression of hundreds of inducible genes encoding pathological mediators. Crosstalk between Sp1 and NF-κB pathways could be pat...
作者:Xiaobing Ye , Yiping Zhu , Juan Cai
来源:[J].Journal of Cancer Research and Therapeutics(IF 0.761), 2015, Vol.11 (6), pp.185-190
摘要:Background: The aim of this meta-analysis was to analyze the relationship of toxicities and clinical benefits of newly approved lenvatinib and sorafenib to thyroid cancer (TC) in patients.Materials and Methods: Three major medical databases, PubMed, EMBASE, and ISI web of sc...
作者:Xiaobing Ye , Shu Fang Liu
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2001, Vol.288 (4), pp.927-932
摘要:Abstract(#br)The pathophysiology of septic shock is characterized by the induction of multiple proinflammatory genes and their products. Transcription factors play key roles in the transcription of these genes. Transcription factors may play important roles in the pathophysi...
作者:Xiaobing Ye , Sun-zhong Mao ...
来源:[J].The American Journal of Pathology(IF 4.522), 2012, Vol.181 (5), pp.1530-1539
摘要:Current animal models of chronic intermittent hypoxia (CIH)-induced atherosclerosis have limitations. Mechanisms of CIH-induced atherosclerosis are poorly understood. This study tested new mouse models of CIH-induced atherosclerosis and defined the role of NF-κB p50 in CIH-i...
作者:Xiaobing Ye , David Wilson ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2006, Vol.343 (2), pp.591-596
摘要:Abstract(#br)Obstructive sleep apnea (OSA) is an important risk factor for cardiovascular morbidity and mortality. The mechanisms through which OSA promotes the development of cardiovascular disease are poorly understood. In this study, we tested the hypotheses that chronic ...
作者:... Dongmei Song , Xiaobing Ye , Shu Fang Liu
来源:[J].Sleep Medicine(IF 3.487), 2013, Vol.14 (2), pp.165-171
摘要:Abstract(#br)Objectives(#br)Patients with obstructive sleep apnea have an impaired endothelium-dependent vasodilator response. The mechanisms underlying this impairment remain unclear. We tested the hypothesis that chronic intermittent hypoxia (CIH) impairs endothelium-depen...
作者:Xiaobing Ye , Kamel Marzouk
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2003, Vol.307 (3), pp.451-458
摘要:Abstract(#br)Studies of the regulation of iNOS expression have provided many contradictory results. Comparing iNOS expression profile between cell types or organs of the same animal under the same experimental conditions may provide an explanation for these conflicting resul...
作者:Xiaobing Ye , Edmund J. Miller
来源:[J].Scientific Reports(IF 2.927), 2014, Vol.4 (1), pp.1546-1554
摘要:Abstract(#br)Endothelial barrier disruption is a hallmark of multiple organ injury (MOI). However, mechanisms governing the restoration of endothelial barrier function are poorly understood. Here, we uncovered an NF-κB-to-AP-1 switch that regulates the transition from barrie...
作者:Xiaobing Ye , Shu Fang Liu
来源:[J].BBA - Molecular Cell Research(IF 4.808), 2006, Vol.1773 (2), pp.243-253
摘要:Abstract(#br)We have previously demonstrated that challenge of rat or mice with lipopolysaccharide (LPS) in vivo promotes Sp1 protein degradation. The protease responsible for the LPS-induced Sp1 degradation has not been identified. In this study, we have identified, charact...

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