全部文献期刊会议图书|学者科研项目
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作者:Xiao-Yin Wang , Dan-Hua Xu
来源:[J].Biotechnology Letters(IF 1.853), 2020, Vol.42 (2), pp.187-196
摘要:Abstract(#br)Objectives(#br)Previously, we have found that the matrix attachment region (MAR) may confer a ‘distance effect’ on transgene expression. This work aims to systematically explore the increased transgene expression in transfected Chinese hamster ovary (CHO) cells ...
作者:Xiao-Yin Wang , Jun-Yi Yin ...
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2018, Vol.107, pp.1310-1319
摘要:Abstract(#br)Hericium erinaceus was extracted with boiling water to obtain the crude polysaccharide (HECP) and refined polysaccharide (HERP). HERP was further purified using gradual ethanol precipitation to obtain five sub-fractions. Their physicochemical properties were evaluate...
作者:Xiao-Yin Wang , Jun-Yi Yin ...
来源:[J].Carbohydrate Polymers(IF 3.479), 2018, Vol.186, pp.100-109
摘要:Abstract(#br)The gastroprotective activity of Hericium erinaceus polysaccharide was investigated in rats. The antioxidant activities were also evaluated. Pre-treatment of polysaccharide could reduce ethanol-induced gastric mucosal lesion and pylorus ligation-induced gastric ...
作者:Xiao-Yin Wang , Rou Xu ...
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2019
摘要:Abstract(#br)Pomelo albedo was extracted with water to obtain the high methoxyl pectin, labeled as PAP. The physicochemical and rheological properties of PAP were determined. The effects of PAP addition on rheological property and thermal stability of konjac glucomannan (KGM) wer...
作者:Xiao-Yin Wang , Rou Xu ...
来源:[J].LWT(IF 2.546), 2019, Vol.115
摘要:Abstract(#br)An alkali-extracted polysaccharide (HEAEP-0.5) was prepared from the water insoluble residue of Hericium erinaceus fruiting body. Effects of concentration, temperature, pH and salts on its rheological property were systematically evaluated. Its physicochemical p...
作者:Wen Wang , Xiao Guo ...
来源:[J].European Journal of Pharmaceutical Sciences(IF 2.987), 2018
摘要:Abstract(#br)Transgene expression in eukaryotic cells suffers from epigenetic effects that result in low or unstable transgene expression and high clonal variability. The use of epigenetic regulators is a promising approach to alleviating such unwanted effects. we investigat...
作者:Xiao-Yin Wang , Jun-He Zhang ...
来源:[J].Scientific Reports(IF 2.927), 2016, Vol.6 (1), pp.316-327
摘要:Abstract(#br)We previously demonstrated that the characteristic sequence of matrix attachment regions (MARs) allows transgenes to be maintained episomally in CHO cells. In the present study, six commonly used promoters from human cytomegalovirus major immediate-early (CMV), ...
作者:... Qiu-Li Sun , Chun-Peng Zhao , Xiao-Yin Wang
来源:[J].Tumor Biology(IF 2.518), 2015, Vol.36 (12), pp.9733-9738
摘要:Abstract(#br)miR-145, a newly identified microRNA molecule, is hypothesized to function as a tumor suppressor, but this activity has not been investigated in esophageal l carcinoma (EC). The aim of this study was to investigate the effect of miR-145 on the biological feature...
作者:Tian-yun Wang , Yan-long Jia ...
来源:[J].Scientific Reports(IF 2.927), 2015, Vol.5 (1), pp.306-312
摘要:Abstract(#br)The therapeutic value of FK228 as a cancer treatment option is well known and various types of cancer have been shown to respond to this drug. However, the complete mechanism of FK228 and the affect it has on histone lysine acetylation and the colon cancer cell prote...
作者:Xiao-Yin Wang , Tian-Yun Wang ...
来源:[J].Biotechnology Letters(IF 1.853), 2014, Vol.36 (10), pp.1937-1943
摘要:Abstract(#br)The β-globin matrix attachment regions (MARs) were inserted into the 5′-site of the eukaryotic expression vector cassette and DNA fragments 350 and 750 bp in length were inserted into the site to generate expression vectors with varying distances between the exp...

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