全部文献期刊会议图书|学者科研项目
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作者:Xiang-Ping Yang , Wan-Li Ma
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)
摘要:Mucus overproduction is an important feature of asthma. Interleukin (IL)-4 is required for allergen-induced airway inflammation and mucus production. MUC5AC gene expression is regulated by transcript factors NF-κB. The intracellular Ca2+ ([Ca2+]i...
作者:... Ran He , Xiang-Ping Yang , Zhao-Hui Tang
来源:[J].Clinical Immunology(IF 3.771), 2018, Vol.192, pp.78-84
摘要:Abstract(#br)In sepsis, the liver plays a crucial role in regulating immune responses and is also a target organ for immune-related injury. Despite the critical function of CD8 + T cells against opportunistic viral infections, the CD8 immune response in the liver during seps...
作者:Xiang-Ping Yang , Di Yu ...
来源:[J].The Journal of Allergy and Clinical Immunology(IF 12.047), 2018, Vol.141 (3), pp.927-937
摘要:Background(#br)The contribution of ectopic lymphoid tissues (eLTs) to local immunoglobulin hyperproduction in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) is unclear.(#br)Objective(#br)We sought to explore the cellular basis, formation mechanisms, and func...
作者:... Yaqun Wu , Zhuoya Li , Xiang-Ping Yang
来源:[J].Oncogene(IF 7.357), 2018, Vol.37 (25), pp.3456-3470
摘要:Abstract(#br)Chemoresistance remains a major obstacle to successful treatment of breast cancer. Although soluble tumor necrosis factor-α (sTNF-α) has been implicated in mediating drug-resistance in human cancers, whether transmembrane tumor necrosis factor-α (tmTNF-Î...
作者:Xiang-Ping Yang , Kan Jiang ...
来源:[J].Scientific Reports(IF 2.927), 2015, Vol.5 (1), pp.1098-1102
摘要:Abstract(#br)The roles of EZH2 in various subsets of CD4+ T cells are controversial and its mechanisms of action are incompletely understood. FOXP3-positive Treg cells are a critical helper T cell subset and dysregulation of Treg generation or function results in syste...
作者:Xiang-Ping Yang , Fred Schaper ...
来源:[J].Journal of Hepatology(IF 9.858), 2005, Vol.43 (4), pp.704-710
摘要:Background/Aims(#br)Interleukin-6 is mandatory for liver regeneration after injury and for the hepatic expression of acute phase proteins and cytochrome P450 enzymes during inflammation. Due to its crucial contribution to the maintenance of homeostasis IL-6 signaling is tightly c...
作者:Xiang-Ping Yang , Yuka Kanno
来源:[J].Cytokine and Growth Factor Reviews(IF 8.831), 2010, Vol.21 (6), pp.425-434
摘要:Abstract(#br)Over the last decade, our understanding of helper/effector T cell differentiation has changed dramatically. The discovery of interleukin (IL-)17-producing T cells (Th17) and other subsets has changed our view of T cell-mediated immunity. Characterization of the signa...
作者:Xiang-Ping Yang , Kiyoshi Hirahara
来源:[J].Trends in Immunology(IF 9.486), 2011, Vol.32 (9), pp.395-401
摘要:T helper (Th)17 cells have been proposed to represent a new CD4 + T cell lineage that is important for host defense against fungi and extracellular bacteria, and the development of autoimmune diseases. Precisely how these cells arise has been the subject of some debate, with...

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