全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:William F. Forrest , Robert R. Graham ...
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (1)Springer
摘要:Large sample sets of whole genome sequencing with deep coverage are being generated, however assembling datasets from different sources inevitably introduces batch effects. These batch effects are not well understood and can be due to changes in the sequencing protocol or bioinfo...
作者:William F. Forrest , Eleanor Feingold
来源:[J].The American Journal of Human Genetics(IF 11.202), 2000, Vol.66 (5), pp.1642-1660Elsevier
摘要:Extreme discordant sibling-pair (EDSP) designs have been shown in theory to be very powerful for mapping quantitative-trait loci (QTLs) in humans. However, their practical applicability has been somewhat limited by the need to phenotype very large populations to find enough ...
作者:William F. Forrest , Ian M. Kasman ...
来源:[J].Cancer Cell(IF 24.755), 2009, Vol.17 (4), pp.362-375Elsevier
摘要:Summary(#br)The neural stem cell marker CD133 is reported to identify cells within glioblastoma (GBM) that can initiate neurosphere growth and tumor formation; however, instances of CD133 − cells exhibiting similar properties have also been reported. Here, we show that some ...
作者:William F. Forrest , Bernard Chow
来源:[J].Journal of Virological Methods(IF 1.9), 2005, Vol.132 (1), pp.48-58Elsevier
摘要:Abstract(#br)Baculovirus protein expression system is a powerful tool for producing recombinant proteins. To optimize conditions for efficient recombinant protein expression, it is important to determine titer of virus stock for arriving at an optimal multiplicity of infection (M...
作者:William F. Forrest , Robert H. Soriano ...
来源:[J].Cancer Cell(IF 24.755), 2006, Vol.9 (3), pp.157-173Elsevier
摘要:Summary(#br)Previously undescribed prognostic subclasses of high-grade astrocytoma are identified and discovered to resemble stages in neurogenesis. One tumor class displaying neuronal lineage markers shows longer survival, while two tumor classes enriched for neural stem cell ma...
作者:William F. Forrest , Joshua S. Kaminker ...
来源:[J].Human Mutation(IF 5.213), 2010, Vol.31 (3), pp.264-271Wiley
摘要:Abstract(#br)Inferring functional consequences is a bottleneck in high‐throughput cancer mutation discovery and genetic association studies. Most polymorphisms and germline mutations are unlikely to have functionally significant consequences. Most cancer somatic mutations do...
作者:William F. Forrest , Peter S. Liu ...
来源:[J].Proceedings of the National Academy of Sciences of the United States of America(IF 9.737), 2013, Vol.110 (28), pp.11379-11384JSTOR
摘要:Ubiquitin is a highly conserved eukaryotic protein that interacts with a diverse set of partners to act as a cellular signaling hub. Ubiquitin′s conformational flexibility has been postulated to underlie its multifaceted recognition. Here we use computational and library-bas...

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