全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Hejun Zhang , Xiongwei Zheng , Wenquan Niu
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (12)DOAJ
摘要:BACKGROUND: Polymorphisms in the APEX nuclease (multifunctional DNA repair enzyme) 1 gene (APEX1) may be involved in the carcinogenesis by affecting DNA repair. We aimed to summarize available data on the association of the APEX1 Asp148Glu (rs1130409) polymorphism with risk of mu...
作者:... Shaoli Chu , Nan Jia , Wenquan Niu
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (11)DOAJ
摘要:BACKGROUND: The hematopoietically-expressed homeobox (HHEX) gene is identified as a promising candidate for type 2 diabetes by genome-wide association studies, triggering plenty of subsequent replications; however, the results are conflicting. We therefore conducted a meta-a...
作者:... Jinxiu Lin , Feng Peng , Wenquan Niu
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (11)DOAJ
摘要:OBJECTIVE: Evidence is mounting suggesting that a strong genetic component underlies aspirin insensitivity. To generate more information, we aimed to evaluate the association of four common polymorphisms (rs3842787, rs20417, rs201184269, rs1126643) from four candidate genes (COX-...
作者:... Yue Qi , Jun Yu , Wenquan Niu
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (6)DOAJ
摘要:BACKGROUND: The association between polymorphisms on 15q25.1 and lung cancer has been widely evaluated; however, the studies have yielded contradictory results. We sought to investigate this inconsistency by performing a comprehensive meta-analysis on two polymorphisms (CHRNA3 ge...
作者:... Jinzi Su , Feng Peng , Wenquan Niu
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (11)DOAJ
摘要:OBJECTIVE: The transradial approach has been used extensively for both diagnostic and interventional coronary procedures; however, there is no universal consensus hitherto on the optimal choice of radial access from either the left or the right artery. We therefore sought to meta...
作者:Wenquan Niu , Zhentian Ni ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (12)DOAJ
摘要:BACKGROUND: Central retinal vein occlusion (CRVO) associates with severe vision outcome and no proven beneficial treatment. Our meta-analysis intended to appraise the efficacy and safety of anti-vascular endothelial growth factor (anti-VEGF) agents in macular edema (ME) following...
作者:... Weifeng Shen , Yanzong Yang , Wenquan Niu
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (10)DOAJ
摘要:BACKGROUND: Growing evidence indicates that advanced glycation end-product receptor (RAGE) might play a contributory role in the pathogenesis of coronary artery disease (CAD). To shed some light from a genetic perspective, we sought to investigate the interactive association of R...
作者:... Weifeng Shen , Jinxiu Lin , Wenquan Niu
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (7)DOAJ
摘要:BACKGROUND: Considerable efforts have been devoted to evaluating the association of the receptor for advanced glycation end-products (gene AGER and protein: RAGE) genetic variants to coronary artery disease (CAD); the results, however, are often irreproducible. To generate more i...
作者:... Nan Jia , Bin Wang , Wenquan Niu
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (1)DOAJ
摘要:BACKGROUND AND OBJECTIVE: Via direct sequencing, we have recently identified six common polymorphisms in angiotensin receptor-like 1 (AGTRL1) gene, and found only two polymorphisms were significantly associated with hypertension in a family-based analysis on 1,015 southern Han Ch...

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