全部文献期刊会议图书|学者科研项目
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作者:Wen-Shyong Tzou , Ying Chu ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (1)DOAJ
摘要:Adaptation of enzymes in a metabolic pathway can occur not only through changes in amino acid sequences but also through variations in transcriptional activation, mRNA splicing and mRNA translation. The heme biosynthesis pathway, a linear pathway comprised of eight consecutive en...
作者:Wen-Shyong Tzou , Margaret Dah-Tsyr Chang ...
来源:[J].BMC Systems Biology(IF 2.982), 2011, Vol.5 (S1)Springer
摘要:Abstract(#br) Background(#br)Hypoxia-inducible factors (HIFs) are transcription factors that play a crucial role in response to hypoxic stress in living organisms. The HIF pathway is activated by changes in cellular oxygen levels and has significant impacts on the regulation of g...
作者:Wei-Po Lee , Wen-Shyong Tzou
来源:[J].Genetics and Molecular Biology(IF 0.744), 2006, Vol.29 (2), pp.408-412DOAJ
摘要:Protein-DNA interactions play a pivotal role in both the transcriptional control and the maintenance of genome integrity, and these are two properties that are closely linked to the development of an organism, differentiation, physiology and to the progression of diseases. Chemic...
作者:Wen-Shyong Tzou , Shiow-Yi Chen ...
来源:[J].Biomaterials(IF 7.604), 2016, Vol.109, pp.12-22Elsevier
摘要:Abstract(#br)Angiogenesis is the process of formation of new blood vessels, which is essential to human biology, and also plays a crucial role in several pathologies such as tumor growth and metastasis, exudative age-related macular degeneration, and ischemia. Vascular endot...
作者:Wen-Shyong Tzou , Shye-Jye Tang ...
来源:[J].Fisheries Science(IF 0.897), 2015, Vol.81 (6), pp.1135-1143Springer
摘要:Abstract(#br)Xylanase is one of the most important hydrolyzed enzymes with multiple functions in industry processing. Since there has been limited research related to β-1,3-xylanse, more attention needs to be paid to discovering an efficient way to produce this enzyme. In th...
作者:... Shing P. Hu , Wen-Shyong Tzou , Chin-Hwa Hu
来源:[J].Neurotoxicology and Teratology(IF 3.181), 2013, Vol.38, pp.92-103Elsevier
摘要:Abstract(#br)Alcohol exposure during embryogenesis results in a variety of developmental disorders. Here, we demonstrate that continuous exposure to 1.5% ethanol causes substantial apoptosis and abrogated retinal and CNS development in zebrafish embryos. Chronic exposure to ethan...
作者:... Shiu-Mei Liu , Wen-Shyong Tzou , Tsuei-Yun Fang
来源:[J].Biochemical Engineering Journal(IF 2.579), 2014, Vol.83, pp.121-128Elsevier
摘要:Abstract(#br)l -Arabinose isomerase (EC 5.3.1.4, l -AI) mainly catalyzes the reversible aldose–ketose isomerization between l -arabinose and l -ribulose. l -AIs can also catalyze other reactions, such as the conversion of d -galactose to d -tagatose. In this study, the araA ...

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