全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Wen Zhang , Yanlin Chen ...
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (1)Springer
摘要:Drug-drug interactions (DDIs) are one of the major concerns in drug discovery. Accurate prediction of potential DDIs can help to reduce unexpected interactions in the entire lifecycle of drugs, and are important for the drug safety surveillance.
作者:Wen Zhang , Xiaopeng Zhu ...
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (13)Springer
摘要:Alternative splicing is the critical process in a single gene coding, which removes introns and joins exons, and splicing branchpoints are indicators for the alternative splicing. Wet experiments have identified a great number of human splicing branchpoints, but many branchpoints...
作者:Wen Zhang , Xiang Yue ...
来源:[J].BMC Systems Biology(IF 2.982), 2017, Vol.11 (6)Springer
摘要:Drug side effects are one of main concerns in the drug discovery, which gains wide attentions. Investigating drug side effects is of great importance, and the computational prediction can help to guide wet experiments. As far as we known, a great number of computational methods h...
作者:Wen Zhang , Kelly O’Brien ...
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer
摘要:Malignant breast cancer with complex molecular mechanisms of progression and metastasis remains a leading cause of death in women. To improve diagnosis and drug development, it is critical to identify panels of genes and molecular pathways involved in tumor progression and malign...
作者:... Wei-Mao Qian , Yu-Ming Chu , Wen Zhang
来源:[J].Journal of Inequalities and Applications(IF 0.822), 2017, Vol.2017 (1)Springer
摘要:In the article, we provide a monotonicity rule for the function \([P(x)+A(x)]/[P(x)+B(x)]\) , where \(P(x)\) is a positive differentiable and decreasing function defined on \((-R, R)\) ( \(R>0\) ), and \(A(x)=\sum ^{\infty}_{n=n_{0}}a_{n}x^{n}\) and \(B(x)=\sum^{\infty }_{n=n_{0}...
作者:Wen Zhang , Hironori Nakano ...
来源:[J].BMC Public Health(IF 2.076), 2017, Vol.17 (1)Springer
摘要:Socioeconomic status (SES) and lifestyle-related factors are determinants of subjective health. However, changes in SES are inevitable in times of natural disaster, while lifestyle-related factors remain modifiable. The aim of this study was to use a cross-sectional approach to e...
作者:... Tingting Zhang , Xiuwen Li , Wen Zhang
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (16)Springer
摘要:Pathogen detection in clinical samples based on 16S metagenomic sequencing technology in microbiology laboratories is an important strategy for clinical diagnosis, public health surveillance, and investigations of outbreaks. However, the implementation of the technology is limite...
作者:Wen Zhang , Jiliang Yin ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:To evaluate the efficacy of cetuximab combined with modified FOLFIRI (mFOLFIRI) as a second-line treatment in metastatic gastric cancer patients and to identify potential biomarkers of clinical outcomes.
作者:Wen Zhang , Tingting Zhao ...
来源:[J].Virology Journal(IF 2.092), 2017, Vol.14 (1)Springer
摘要:Sapovirus (SaV), a member of the family Caliciviridae , is an etiologic agent of gastroenteritis in humans and pigs. To date, both intra- and inter-genogroup recombinant strains have been reported in many countries except for China. Here, we report an intra-genogroup recombinatio...

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