全部文献期刊会议图书|学者科研项目
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作者:Wen Zhang , Yanlin Chen ...
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (1)
摘要:Drug-drug interactions (DDIs) are one of the major concerns in drug discovery. Accurate prediction of potential DDIs can help to reduce unexpected interactions in the entire lifecycle of drugs, and are important for the drug safety surveillance.
作者:Wen Zhang , Xiaopeng Zhu ...
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (13)
摘要:Alternative splicing is the critical process in a single gene coding, which removes introns and joins exons, and splicing branchpoints are indicators for the alternative splicing. Wet experiments have identified a great number of human splicing branchpoints, but many branchpoints...
作者:Wen Zhang , Kelly O’Brien ...
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)
摘要:Malignant breast cancer with complex molecular mechanisms of progression and metastasis remains a leading cause of death in women. To improve diagnosis and drug development, it is critical to identify panels of genes and molecular pathways involved in tumor progression and malign...
作者:Wen Zhang , Lingling Wu
来源:[J].Chromatographia(IF 1.437), 2017, Vol.80 (11), pp.1659-1667
摘要:Freeze-dried biological samples used for the determination of organotin compounds (OTCs) involve complicated or tedious pretreatment (e.g., freeze-drying) that may result in loss of analyst or contamination. In the present study, a rapid and accurate method for determination...
作者:... Tingting Zhang , Xiuwen Li , Wen Zhang
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (16)
摘要:Pathogen detection in clinical samples based on 16S metagenomic sequencing technology in microbiology laboratories is an important strategy for clinical diagnosis, public health surveillance, and investigations of outbreaks. However, the implementation of the technology is limite...
作者:Wen Zhang , Xiaomin Xiong ...
来源:[J].European Journal of Drug Metabolism and Pharmacokinetics(IF 0.944), 2017, Vol.42 (4), pp.669-676
摘要:Ophiopogonin D (OPD) is one of the main active ingredients of SMI (Shenmai injection) which is widely used in clinical practice in China. Our previous study indicated that OPD might be transported from blood into liver mediated by organic anion transporting polypeptides (OATPs/oa...
作者:Wen Zhang , Qihua Zhao ...
来源:[J].Landslides(IF 2.093), 2017, Vol.14 (3), pp.1253-1263
摘要:This study attempts to determine the critical slip surface of a fractured rock slope in Laohuding Quarry in Tianjin City, China. Fractures in a 30 × 20 m cross section of Laohuding slope are generated based on stochastic mathematics. Fracture network modeling reflects only t...
作者:Wen Zhang , Hui Zheng ...
来源:[J].Ionics(IF 1.674), 2017, Vol.23 (8), pp.2103-2112
摘要:Nanocomposite polymers based on phosphonic acid functionalized carbon nanotubes (CNT-POH) and sulfonated poly(ether ether ketone) (SPEEK) have been fabricated and employed as highly efficient proton exchange membranes. CNT-POH were synthesized through the grafting of carbon nanot...
作者:Wen Zhang , Victoria Pease ...
来源:[J].Geosciences Journal(IF 0.618), 2017, Vol.21 (5), pp.667-682
摘要:The Mingshui and Shuangjingzi granitic plutons are exposed in the northern Beishan area, in the southern Central Asia Orogenic Belt. U-Pb zircon dating indicates that Mingshui secondary intrusive lithosfacies and Shuangjingzi quartz monzodiorite formed at 328 ± 2 Ma and 272 ...

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