全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Shraddha Thakkar , Weida Tong , Nicholas Petrick
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (14)Springer
摘要:Recent breakthroughs in molecular biology and next generation sequencing technologies have led to the expenential growh of the sequence databases. Researchrs use BLAST for processing these sequences. However traditional software parallelization techniques (threads, message passin...
作者:Weida Tong , Yongxiang Zhao ...
来源:[J].Science China Life Sciences(IF 2.024), 2017, Vol.60 (2), pp.178-188Springer
摘要:Abstract(#br)Human and mouse orthologs are expected to have similar biological functions; however, many discrepancies have also been reported. We systematically compared human and mouse orthologs in terms of alternative splicing patterns and expression profiles. Human-mouse ortho...
作者:... Leming Shi , Weida Tong , Baitang Ning
来源:[J].Science China Life Sciences(IF 2.024), 2019, Vol.62 (7), pp.895-904Springer
摘要:Abstract(#br)High-throughput next generation sequencing (NGS) is a shotgun approach applied in a parallel fashion by which the genome is fragmented and sequenced through small pieces and then analyzed either by aligning to a known reference genome or by de novo assembly with...
作者:Weida Tong , Baitang Ning ...
来源:[J].Science China Life Sciences(IF 2.024), 2019, Vol.62 (7), pp.937-946Springer
摘要:Abstract(#br)RNA sequencing (RNA-seq) has greatly facilitated the exploring of transcriptome landscape for diverse organisms. However, transcriptome reconstruction is still challenging due to various limitations of current tools and sequencing technologies. Here, we introduc...
作者:... Zhichao Liu , Ruili Huang , Weida Tong
来源:[J].BMC Bioinformatics(IF 3.024), 2016, Vol.17 (13)Springer
摘要:Abstract(#br) Background(#br)All biological processes are inherently dynamic. Biological systems evolve transiently or sustainably according to sequential time points after perturbation by environment insults, drugs and chemicals. Investigating the temporal behavior of molec...
作者:... Huixiao Hong , Weida Tong , Wen Zou
来源:[J].BMC Bioinformatics(IF 3.024), 2016, Vol.17 (1)Springer
摘要:Abstract(#br) Background(#br)Next-generation sequencing (NGS) technologies have provided researchers with vast possibilities in various biological and biomedical research areas. Efficient data mining strategies are in high demand for large scale comparative and evolutional studie...
作者:Weida Tong , William Mattes ...
来源:[J].BMC Bioinformatics(IF 3.024), 2015, Vol.16 (13)Springer
摘要:Abstract(#br) Background(#br)As the major histocompatibility complex (MHC), human leukocyte antigens (HLAs) are one of the most polymorphic genes in humans. Patients carrying certain HLA alleles may develop adverse drug reactions (ADRs) after taking specific drugs. Peptides play ...
作者:... Roger Perkins , LeMing Shi , WeiDa Tong
来源:[J].Science China Life Sciences(IF 2.024), 2013, Vol.56 (2), pp.110-118Springer
摘要:Abstract(#br)Realizing personalized medicine requires integrating diverse data types with bioinformatics. The most vital data are genomic information for individuals that are from advanced next-generation sequencing (NGS) technologies at present. The technologies continue to adva...

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