全部文献期刊会议图书|学者科研项目
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作者:... Yong-Yi Zhang , You-Zhi Zhang , Wei-Dong Mi
来源:[J].Journal of Neuroinflammation(IF 4.351), 2017, Vol.14 (1)
摘要:Considerable evidence has shown that neuroinflammation and oxidative stress play an important role in the pathophysiology of postoperative cognitive dysfunction (POCD) and other progressive neurodegenerative disorders. Increasing evidence suggests that acetaminophen (APAP) has un...
作者:... Qiang Fu , Zhi-peng Xu , Wei-dong Mi
来源:[J].Brain Research Bulletin(IF 2.935), 2017, Vol.130, pp.274-282
摘要:Abstract(#br)Postoperative cognitive dysfunction (POCD) is characterized by cognitive impairments in patients after surgery. Hippocampal neuroinflammation induced by surgery is highly associated with POCD. Phosphodiesterase-4 (PDE4) is an enzyme that specifically hydrolyses cycli...
作者:... Li-Ming Zhang , Yun-Feng Li , Wei-Dong Mi
来源:[J].International Immunopharmacology(IF 2.417), 2018, Vol.65, pp.438-447
摘要:Abstract(#br)Neuroinflammation is believed to be one of the primary causes of cognitive impairment. Previous studies showed that the antioxidant vitamin C (Vit C) performs many beneficial functions such as immunostimulant and anti-inflammatory actions, but its role in inflam...
作者:... Xiao-Ping Wang , Wei-Dong Mi , Wei-Wu Fang
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (4)
摘要:Posterior spinal instrumentation and fusion surgery in school-aged children and adolescents is associated with the potential for massive intraoperative blood loss, which requires significant allogeneic blood transfusion. Until now, the intraoperative use of the cell saver has bee...
作者:... Lin-bo Jiao , Ya-qun Ma , Wei-Dong Mi
来源:[J].Brain Research Bulletin(IF 2.935), 2016, Vol.121, pp.192-200
摘要:Abstract(#br)Translocator protein 18 kDa (TSPO) is now an attractive drug target for controlling neuroinflammation. Studies applying TSPO ligands to neurodegenerative diseases, especially Alzheimer’s disease (AD), were rare. Our study was aimed to evaluate the effect of PK11...
作者:Wei-dong Mi , Wei-xiu Yuan ...
来源:[J].BMC Anesthesiology(IF 1.188), 2015, Vol.16 (1)
摘要:Abstract(#br) Background(#br)The settings of mechanical ventilation, like tidal volume (VT), occasionally need to be adjusted in the process of anesthesia for some special reasons. The aim of this study was therefore to assess the relationship between pulse pressure variations (P...
作者:... Li-Na An , Wei-Wu Fang , Wei-Dong Mi
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2014, Vol.447 (1), pp.95-100
摘要:Abstract(#br)Corticosterone inhibits the proliferation of hippocampal neural stem cells (NSCs). The removal of corticosterone-induced inhibition of NSCs proliferation has been reported to contribute to neural regeneration. Leptin has been shown to regulate brain development, impr...
作者:... Hong Zhang , Yun-Feng Li , Wei-Dong Mi
来源:[J].Neuroscience Letters(IF 2.026), 2013, Vol.547, pp.53-58
摘要:Abstract(#br)Midazolam is a benzodiazepine derivative drug that has powerful anxiolytic, amnestic, hypnotic, and sedative properties. The cytoprotective effect of midazolam on brain astrocytes is poorly understood. This study aimed to investigate the cytoprotective effect of...
作者:... Li-Ming Zhang , Wei-Dong Mi , Yun-Feng Li
来源:[J].Neural Regeneration Research(IF 0.144), 2018, Vol.13 (11), pp.1937-1944
摘要:Translocator protein has received attention for its involvement in the pathogenesis of depression. This study assessed the effects of the new translocator protein ligand, YL-IPA08, on alleviating inflammation-induced depression-like behavior in mice and investigated its mech...
作者:... Chao Zhu , Yan-Hong Liu , Wei-Dong Mi
来源:[J].Neurochemical Research(IF 2.125), 2016, Vol.41 (7), pp.1587-1603
摘要:Abstract(#br)Stromal cell-derived factor 1 (SDF-1)/chemokine CXC motif ligand 12 (CXCL12), a chemokine that is upregulated in dorsal root ganglion (DRG) during chronic pain models, has recently been found to play a central role in pain hypersensitivity. The purpose of presen...

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