全部文献期刊会议图书|学者科研项目
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作者:Wei-Cheng Lian , Ta-Wen Hsu
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (8)
摘要:BACKGROUND: This population-based study investigated the relationship between individual and neighborhood socioeconomic status (SES) and mortality rates for major cancers in Taiwan. METHODS: A population-based follow-up study was conducted with 20,488 cancer patients diagnosed in...
作者:... Pesus Chou , Wei-Cheng Lian , Ching-Chih Lee
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (4)
摘要:BACKGROUND: Although much attention has been focused on the association between chronic hyperglycemia and cerebrovascular diseases in type 2 diabetes mellitus (DM) patients, there is no data regarding the risk of ischemic stroke after a hyperosmolar hyperglycemic state (HHS) atta...
作者:Wei-Cheng Lian , Dee Pei ...
来源:[J].Annals of Saudi Medicine(IF 1.103), 2016, Vol.36 (3), pp.203-209
摘要:BACKGROUND: Type 2 diabetes mellitus (T2DM) is characterized by impaired insulin sensitivity (Si) and insulin secretion. Previous studies may have underestimated differences in the incidence of risk factors in insulin-sensitive diabetes mellitus (IS-DM) and insultin-resistan...
作者:Wei-Cheng Lian , Li-Ching Hsu
来源:[J].Virus Research(IF 2.745), 1997, Vol.51 (2), pp.173-181
摘要:Abstract(#br)Two different plaque variants of Japanese encephalitis virus were selected from a wild-type Taiwanese isolate using Vero cells. One variant was found to exhibit small plaque morphology with retarded virus replication kinetics in Vero cells, and was demonstrated to be...
作者:Wei-Cheng Lian , Ih-Jen-Su ...
来源:[J].Vaccine(IF 3.492), 2011, Vol.30 (4), pp.703-711
摘要:Abstract(#br)Enterovirus 71 (EV71) has recently emerged as an important neurotropic virus in Asia because effective medications and prophylactic vaccine against EV71 infection are not available. Based on the success of inactivated poliovirus vaccine, the Vero cell-based chemicall...
作者:Wei-Cheng Lian , Li-Ching Hsu ...
来源:[J].Virus Research(IF 2.745), 1998, Vol.55 (1), pp.83-91
摘要:Abstract(#br)The antigenic properties of nine wild-type Japanese encephalitis viruses isolated in Taiwan during 1990–1994 were investigated by comparison with two inactivated vaccine strains (Beijing-1, Nakayama-NIH). All of the nine Taiwanese isolates were found to induce h...
作者:Wei-Cheng Lian , Michael Butler
来源:[J].Vaccine(IF 3.492), 2006, Vol.25 (1), pp.19-24
摘要:Abstract(#br)Developing an effective vaccine against enterovirus 71 (EV71) infection provides the best means to control the disease. We have previously reported that large-scale preparation of a low immunogenic EV71 strain can be achieved using serum free microcarrier Vero c...
作者:Wei-Cheng Lian , Chi-Ju Chen ...
来源:[J].Vaccine(IF 3.492), 2006, Vol.24 (16), pp.3100-3108
摘要:Abstract(#br)The recombinant nucleocapsid (rN) protein of the coronavirus (CoV) responsible for severe acute respiratory syndrome (SARS) was cloned and expressed in Escherichia coli , extracted from cell lysates containing 6 M urea, then purified by Ni 2+ -affinity chromatog...
作者:Suh-Chin Wu , Chia-Chyi Liu , Wei-Cheng Lian
来源:[J].Vaccine(IF 3.492), 2004, Vol.22 (29), pp.3858-3864
摘要:Abstract(#br)Enterovirus 71 (EV71) is an enterovirus that could lead to severe neurological disorders and fatalities. The inactivated vaccine is an appropriate EV71 vaccine format for meeting current needs. Large-scale preparation of the inactivated EV71vaccine depends on a ...

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