全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Walter Wahli , Hervé Guillou
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2016, Vol.17 (10)DOAJ
摘要:The liver plays a central role in the regulation of fatty acid metabolism, which is highly sensitive to transcriptional responses to nutrients and hormones. Transcription factors involved in this process include nuclear hormone receptors. One such receptor, PPARα, which is h...
作者:... Vladimir A. Kuznetsov , Hervé Guillou , Walter Wahli
来源:[J].Scientific Reports(IF 2.927), 2018, Vol.8 (1), pp.1-15DOAJ
摘要:Abstract The intestine is key for nutrient absorption and for interactions between the microbiota and its host. Therefore, the intestinal response to caloric restriction (CR) is thought to be more complex than that of any other organ. Submitting mice to 25% CR during 14 days...
作者:Walter Wahli , Daniel Meztger ...
来源:[J].Lipids in Health and Disease(IF 2.015), 2011, Vol.10 (1)Springer
摘要:Abstract(#br) Background(#br)Long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFA) of marine origin exert multiple beneficial effects on health. Our previous study in mice showed that reduction of adiposity by LC n-3 PUFA was associated with both, a shift in adipose tissu...
作者:Liliane Michalik , Walter Wahli
来源:[J].PPAR Research(IF 2.685), 2008, Vol.2008DOAJ
摘要:Lipid mediators can trigger physiological responses by activating nuclear hormone receptors, such as the peroxisome proliferator-activated receptors (PPARs). PPARs, in turn, control the expression of networks of genes encoding proteins involved in all aspects of lipid metabolism....
作者:David Brawand , Walter Wahli , Henrik Kaessmann
来源:[J].PLoS Biology(IF 11.452), 2008, Vol.6 (3)DOAJ
摘要:Embryonic development in nonmammalian vertebrates depends entirely on nutritional reserves that are predominantly derived from vitellogenin proteins and stored in egg yolk. Mammals have evolved new resources, such as lactation and placentation, to nourish their developing and ear...
作者:Nguan S Tan , Walter Wahli
来源:[J].EMBO Molecular Medicine(IF 7.795), 2014, Vol.6 (4), pp.431-433Wiley
摘要:The nuclear factor erythroid 2‐related factor 2 (Nrf2) is best known for its role in resistance to oxidant stress. In this issue of EMBO Molecular Medicine , Nrf2‐prolonged genetic activation is shown with devastating effects on skin homeostasis. The study provides novel mol...
作者:Walter Wahli , Colin N. A. Palmer
来源:[J].PPAR Research(IF 2.685), 2015, Vol.2015Hindawi
摘要:Peroxisome proliferator activated receptors alpha (PPAR α ) and delta (PPAR δ ) belong to the nuclear receptor superfamily. PPAR α is a target of well established lipid-lowering drugs. PPAR δ (also known as PPAR β / δ ) has been investigated as a promising antidiabetic ...
作者:Walter Wahli , Françoise Rohner-Jeanrenaud
来源:[J].Metabolism(IF 3.096), 2018Elsevier
摘要:Abstract(#br)Background(#br)Oleoylethanolamide (OEA) is an endocannabinoid that controls food intake, energy expenditure and locomotor activity. Its anorexigenic effect appears to be mediated by PPARα, but the tissue where the presence of this receptor is required for OEA to...

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