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作者:... Vera Luiza Capelozzi , Walcy Rosolia Teodoro , Natalino Hajime Yoshinari
来源:[J].Clinics(IF 2.058), 2009, Vol.64 (6), pp.577-583DOAJ
摘要:INTRODUCTION/OBJECTIVES: Systemic sclerosis, or scleroderma, is a rheumatic disease characterized by autoimmunity, vasculopathy, and fibrosis of the skin and several internal organs. In the present study, our aim was to assess the skin alterations in animals with scleroderma...
作者:Walcy Rosolia Teodoro , Ana Paula Pereira Velosa
来源:[J].Revista Brasileira de Reumatologia(IF 0.864), 2006, Vol.46 (3), pp.194-198DOAJ
摘要:As proteínas da matriz extracelular (MEC) e seus componentes estão sendo amplamente estudados na literatura médica, assim como sua relação com o remodelamento tecidual presente nas doenças reumáticas. Neste artigo, mostramos a importância do estudo do colágeno do tipo V...
作者:... Vera Luíza Capelozzi , Walcy Rosolia Teodoro , Natalino H. Yoshinari
来源:[J].Revista Brasileira de Reumatologia(IF 0.864), 2007, Vol.47 (6), pp.401-410DOAJ
摘要:OBJETIVO: Estabelecer as alterações morfológicas e o remodelamento do tecido cartilaginoso na progressão da osteoartrite (OA) experimental para estudar o efeito do difosfato de cloroquina na cartilagem osteoartrítica. MÉTODOS: A osteoartrite experimental foi induzida em...
作者:Walcy Rosolia Teodoro , Silvia Rodrigues ...
来源:[J].Human Pathology(IF 2.843), 2018, Vol.75, pp.104-115Elsevier
摘要:Summary(#br)This study analyzed the type 1 and type 2 T helper (Th1/Th2) cytokines (including interleukins), immune cellular, matrix profile, and pathogens in granulomas with unexplained etiology compared to those with infectious and noninfectious etiology. Surgical lung bio...
作者:Walcy Rosolia Teodoro , Evandro Sobroza de Mello ...
来源:[J].Journal of Pediatric Surgery(IF 1.383), 2016, Vol.51 (3), pp.379-385Elsevier
摘要:Abstract(#br)Background(#br)Biliary atresia (BA) is a cholestatic liver disease of children that progresses to hepatic fibrosis. BA is the main indication of pediatric liver transplantation (LTx). Histopathological markers in liver biopsies could be useful for predicting progress...
作者:... Alexandre Todorovic Fabro , Walcy Rosolia Teodoro , Vera Luiza Capelozzi
来源:[J].Archivum Immunologiae et Therapiae Experimentalis(IF 2.378), 2016, Vol.64 (4), pp.321-329Springer
摘要:Abstract(#br)Type V collagen (Col V) is a “minor” component of normal lung extracellular matrix, which is subjected to decreased and abnormal synthesis in human lung infiltrating adenocarcinoma. We previously reported that a direct link between low amounts of Col V and decre...
作者:Walcy Rosolia Teodoro , Natalino Hajime Yoshinari
来源:[J].Burns(IF 1.799), 2008, Vol.35 (5), pp.701-706Elsevier
摘要:Abstract(#br)Fibroblasts are thought to be partially responsible for the persisting contractile forces that result in burn contractures. Using a monolayer cell culture and fibroblast populated collagen lattice (FPCL) three-dimensional model we subjected hypertrophic scar and...
作者:Walcy Rosolia Teodoro , Solange Carrasco ...
来源:[J].Human Pathology(IF 2.843), 2009, Vol.41 (2), pp.239-248Elsevier
摘要:Summary(#br)Collagen V shows promise as an inducer of the death response via caspases. Remodeling of the microenvironment by collagen V, tumoral/vascular apoptosis, and the immune response were evaluated, based on the prognosis of 65 patients with surgically excised non-small cel...
作者:Walcy Rosolia Teodoro , Cristiane Carla Oliveira ...
来源:[J].Archives of Dermatological Research(IF 2.708), 2006, Vol.298 (2), pp.51-57Springer
摘要:Abstract(#br)Recently, we discovered that New Zealand rabbits immunized with human type V collagen plus Freund’s adjuvant present fibrosis and vasculitis of organs usually affected by systemic sclerosis. In this way, we studied the fibrillogenesis process to identify possibl...
作者:Walcy Rosolia Teodoro , Cristiane Carla Oliveira ...
来源:[J].Archives of Dermatological Research(IF 2.708), 2007, Vol.299 (4), pp.177-189Springer
摘要:Abstract(#br)Our aim was to study skin remodeling and autoantibody production in an experimental model of scleroderma (SSc), following nasal tolerance with human type V collagen (Col V). Female New Zealand rabbits ( n = 12) were immunized with two doses of 1 mg/ml of Col V i...

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