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作者:... Stan Heptinstall , William R. Dunn , Vera Ralevic
来源:[J].Vascular Pharmacology(IF 3.212), 2018, Vol.103-105, pp.36-46
摘要:Abstract(#br)Aims(#br)UDP-sugars can act as extracellular signalling molecules, but relatively little is known about their cardiovascular actions. The P2Y 14 receptor is a G i/o -coupled receptor which is activated by UDP-glucose and related sugar nucleotides. In this study we so...
作者:Vera Ralevic , William R. Dunn
来源:[J].Autonomic Neuroscience: Basic and Clinical(IF 1.846), 2015, Vol.191, pp.48-66
摘要:Abstract(#br)There are nineteen different receptor proteins for adenosine, adenine and uridine nucleotides, and nucleotide sugars, belonging to three families of G protein-coupled adenosine and P2Y receptors, and ionotropic P2X receptors. The majority are functionally expressed i...
作者:... Stephen P.H. Alexander , Vera Ralevic , Richard E. Roberts
来源:[J].Pharmacology and Therapeutics(IF 7.793), 2016, Vol.158, pp.101-113
摘要:Abstract(#br)In recent years, it has become apparent that the gaseous pollutant, hydrogen sulphide (H 2 S) can be synthesised in the body and has a multitude of biological actions. This review summarizes some of the actions of this ‘gasotransmitter’ in influencing the smooth...
作者:Vera Ralevic , Abebech Belai , Geoffrey Burnstock
来源:[J].European Journal of Pharmacology(IF 2.592), 1995, Vol.286 (2), pp.193-199
摘要:Abstract(#br)Mesenteric arterial function was assessed in constantly perfused preparations isolated from rats 12 weeks after treatment with streptozotocin (65 mg kg −1 , i.p.) to induce diabetes. Frequency-dependent vasoconstrictor responses to electrical field stimulation o...
作者:Vera Ralevic
来源:[J].European Journal of Pharmacology(IF 2.592), 2000, Vol.387 (3), pp.287-293
摘要:Abstract(#br)The aim of the present study was to determine whether there are prejunctional inhibitory P2 purine receptors on sympathetic nerves in the hamster isolated perfused mesenteric arterial bed. Adenosine 5′- O -(3-thiotriphosphate (ATPγS; 10 μM), adenosine 5′- O...
作者:Vera Ralevic
来源:[J].European Journal of Pharmacology(IF 2.592), 2003, Vol.472 (1), pp.1-21
摘要:Abstract(#br)Cannabinoids are cell membrane-derived signalling molecules that are released from nerves, blood cells and endothelial cells, and have diverse biological effects. They act at two distinct types of G-protein-coupled receptors, cannabinoid CB 1 and CB 2 receptors....
作者:Vera Ralevic , David A Kendall
来源:[J].European Journal of Pharmacology(IF 2.592), 2002, Vol.444 (3), pp.171-181
摘要:Abstract(#br)The effects of cannabinoids on sympathetic neurotransmission in the rat isolated perfused mesenteric arterial bed, were investigated. Electrically evoked sympathetic neurogenic vasocontraction was inhibited by the cannabinoid receptor agonists 11-hydroxy-dimethy...
作者:Vera Ralevic , Gjumrach Aliev , Geoffrey Burnstock
来源:[J].European Journal of Pharmacology(IF 2.592), 1996, Vol.313 (3), pp.221-227
摘要:Abstract(#br)Vascular function of Donryu rats fed on a normal or cholesterol-supplemented diet was examined in the isolated perfused mesenteric arterial bed and portally perfused liver. In mesenteric preparations, frequency-dependent vasoconstriction to electrical field stim...
作者:Vera Ralevic , Jeffrey C Jerman ...
来源:[J].Biochemical Pharmacology(IF 4.576), 2003, Vol.65 (1), pp.143-151
摘要:Abstract(#br)This study compared the actions of members of five different chemical classes of vanilloid agonists at the recombinant rat vanilloid VR1 receptor expressed in HEK293 cells, and at endogenous vanilloid receptors on dorsal root ganglion cells and sensory nerves in...

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