全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Tzu-Hurng Cheng , Shih-Hurng Loh ...
来源:[J].Journal of Biomedical Science, 2017, Vol.24 (1)Springer
摘要:This study investigated whether lipopolysaccharide (LPS) increase protease-activated receptor-2 (PAR-2) expression and enhance the association between PAR-2 expression and chemokine production in human vascular endothelial cells (ECs).
作者:Tzu-Hurng Cheng , Yueh-Hsiung Kuo ...
来源:[J].Pharmacological Reports(IF 1.965), 2015, Vol.67 (6), pp.1049-1054Elsevier
摘要:Abstract(#br)Background(#br)Hinokiol is a naturally occurring diterpenoid compound isolated from plants such as Taiwania cryptomerioides . Anti-oxidation, anti-cancer, and anti-inflammation effects of this compound have been reported. It is not yet known if hinokiol affects ...
作者:Tzu-Hurng Cheng , Zhong-Min Liu ...
来源:[J].Pharmacological Reports(IF 1.965), 2014, Vol.66 (4), pp.576-584Elsevier
摘要:Abstract(#br)Background(#br)Strong P2X7 receptor (P2X7R) activation causes Ca 2+ overload and consequent cell death. We previously showed that depletion of Ca 2+ stores and endoplasmic reticulum (ER) stress in differentiated NG108-15 neuronal cells contributed to P2X7R-media...
作者:Tzu-Hurng Cheng , Neng-Lang Shih ...
来源:[J].Journal of Biomedical Science(IF 2.458), 2005, Vol.12 (1), pp.123-133Springer
摘要:Abstract(#br)Endothelin-1 (ET-1) has been found to increase cardiac β -myosin heavy chain ( β -MyHC) gene expression and induce hypertrophy in cardiomyocytes. ET-1 has been demonstrated to increase intracellular reactive oxygen species (ROS) in cardiomyocytes. The exact mole...
作者:... Shih-Hurng Loh , Jaung-Geng Lin , Tzu-Hurng Cheng
来源:[J].Journal of Biomedical Science(IF 2.458), 2004, Vol.11 (1), pp.27-36Springer
摘要:Abstract(#br)It is well documented that 17β-estradiol (E 2 ) exerts a cardiovascular protective effect. A possible role of E 2 in the regulation of endothelin-1 (ET-1) production has been reported. However, the complex mechanisms by which E 2 inhibits ET-1 expression are not...
作者:... Jong-Shiaw Jin , Tzu-Hurng Cheng , Jin-Jer Chen
来源:[J].Journal of Biomedical Science(IF 2.458), 2002, Vol.9 (3), pp.198-205Springer
摘要:Abstract(#br)Intracellular pH (pH i ) exerts considerable influence on cardiac contractility and rhythm. Over the last few years, extensive progress has been made in understanding the system that controls pH i in animal cardiomyocytes. In addition to the housekeeping Na + -H...
作者:... Yen-Ling Chen , Hong-Jye Hong , Tzu-Hurng Cheng
来源:[J].Journal of Biomedical Science(IF 2.458), 2004, Vol.11 (1), pp.11-18Springer
摘要:Abstract(#br)The myocardial protective effects of trilinolein, isolated from the traditional Chinese herb Sanchi (Panax notoginseng) , are thought to be related to its antioxidant activity. However, the intracellular mechanism underlying the protective effect of trilinolein ...
作者:Tzu-Hurng Cheng , Yung-Ho Hsu
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (6)DOAJ
摘要:Epithelial-mesenchymal transition (EMT) occurs in stressed tubular epithelial cells, contributing to renal fibrosis. Initial mechanisms promoting EMT are unknown. Pressure force is an important mechanism contributing to the induction and progression of renal fibrogenesis in ...
作者:... Tzu-Hui Su , Yu-Wen Chen , Tzu-Hurng Cheng
来源:[J].Pharmacological Reports(IF 1.965), 2012, Vol.64 (3), pp.739-744Elsevier
摘要:Abstract(#br)Background(#br)Although diphenidol has long been deployed as an anti-emetic and anti-vertigo drug, its mechanism of action remains unclear. In particular, little is known as to how diphenidol affects neuronal ion channels. Recently, we showed that diphenidol blocked ...
作者:Tzu-Hurng Cheng , Chao-Chin Chuang
来源:[J].Journal of Pharmacological Sciences(IF 2.15), 2003, Vol.91 (1), pp.53-60Elsevier
摘要:Abstract(#br)Hydrogen peroxide (H 2 O 2 ) and its metabolites have been shown to exert complex effects on the cardiac muscle during cardiac ischemia/reperfusion. The aim of the present study, by perfusing H 2 O 2 or/and different scavengers of oxygen free radicals (OFRs) int...

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