全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Sigrid S. Skånland , Sébastien Wälchli , Tone F. Gregers
来源:[J].Toxins(IF 2.129), 2013, Vol.5 (5), pp.969-982DOAJ
摘要:The AB plant toxin ricin binds both glycoproteins and glycolipids at the cell surface via its B subunit. After binding, ricin is endocytosed and then transported retrogradely through the Golgi to the endoplasmic reticulum (ER). In the ER, the A subunit is retrotranslocated to the...
作者:Tone F. Gregers , Oddmund Bakke ...
来源:[J].Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics(IF 2.875), 2019, Vol.30, pp.333-346Elsevier
摘要:Abstract(#br)The genetic repertoire underlying teleost immunity has been shown to be highly variable. A rare example is Atlantic cod and its relatives Gadiformes that lacks a hallmark of vertebrate immunity: Major Histocompatibility Complex class II. No immunological studies so f...
作者:... Oddmund Bakke , Johanna Olweus , Tone F. Gregers
来源:[J].European Journal of Immunology(IF 4.97), 2014, Vol.44 (3), pp.774-784Wiley
摘要:Protective T‐cell responses depend on efficient presentation of antigen (Ag) in the context of major histocompatibility complex class I (MHCI) and class II (MHCII) molecules. Invariant chain (Ii) serves as a chaperone for MHCII molecules and mediates trafficking to the endos...
作者:Tone F. Gregers , Tommy W. Nordeng ...
来源:[J].European Journal of Immunology(IF 4.97), 2003, Vol.33 (2), pp.277-286Wiley
摘要:Abstract(#br)The MHC class II‐associated invariant chain (Ii) has several important functions in antigen presentation. In this study, we have examined the effect of Iip33 expression on endocytic transport and antigen presentation. We find that degradation of both endocytosed...
作者:Tone F. Gregers , Randi H. Sandin ...
来源:[J].European Journal of Immunology(IF 4.97), 2006, Vol.36 (1), pp.129-138Wiley
摘要:Abstract(#br)There are potentially two binding sites for C1q on IgG, one on each CH2 domain of the gamma heavy chains, close to the lower hinge region. It is not clear whether the presence and involvement of both the C1q binding sites is necessary to induce the ac...
作者:... Sissel Jentoft , Tone F. Gregers , Kjetill S. Jakobsen
来源:[J].PLOS ONE(IF 3.73), 2013, Vol.8 (9)PLOS
摘要:Genes encoding the major histocompatibility complex (MHC) have been thought to play a vital role in the adaptive immune system in all vertebrates. The discovery that Atlantic cod ( Gadus morhua ) has lost important components of the MHC II pathway, accompanied by an unusually hig...

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