全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Alicja Pakiet , Tomasz Sledzinski , Adriana Mika
来源:[J].Molecules(IF 2.428), 2019, Vol.24 (8)DOAJ
摘要:Oxylipins are potent lipid mediators derived from polyunsaturated fatty acids, which play important roles in various biological processes. Being important regulators and/or markers of a wide range of normal and pathological processes, oxylipins are becoming a popular subject...
作者:Agnieszka Dettlaff-Pokora , Tomasz Sledzinski , Julian Swierczynski
来源:[J].Journal of Applied Biomedicine(IF 0.978), 2015, Vol.13 (2), pp.105-112Elsevier
摘要:Abstract(#br)Leptin down-regulates orexigenic and up-regulates anorexigenic neuropeptide gene expression in hypothalamus. Surgical removal of adipose tissue leads to decrease in circulating leptin concentrations in rats. In the present study, we tested: (a) regulation of neu...
作者:... Michał Chmielewski , Piotr Stepnowski , Tomasz Sledzinski
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2017, Vol.41 (2), pp.722-730DOAJ
摘要:Backgrounds/Aims: Colorectal cancer (CRC) cells show some alterations of lipid metabolism. Elongation of fatty acids (FA) has not been studied in CRC tissues thus far. The aim of this study was to verify if CRC specimens and normal colon mucosa differ in terms of their levels of ...
作者:... Monika Proczko-Stepaniak , Lukasz Kaska , Tomasz Sledzinski
来源:[J].Scientific Reports(IF 2.927), 2017, Vol.7 (1), pp.1-9DOAJ
摘要:Abstract Routine laboratory lipid assays include simple measurements of total cholesterol, triacylglycerols and HDL. However, lipids are a large group of compounds involved in many metabolic pathways, and their alterations may have serious health consequences. In this study, we u...
作者:Agnieszka Dettlaff-Pokora , Tomasz Sledzinski , Julian Swierczynski
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2015, Vol.36 (5), pp.1767-1777DOAJ
摘要:Background/Aims: The aim of this study was to explain the molecular basis for elevated concentrations of circulating triglycerides (TAGs) after partial surgical removal of adipose tissue (lipectomy) in rats. Methods: The levels of mRNA and protein: a) involved in synthesis of fat...
作者:Tomasz Sledzinski , Elzbieta Goyke
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2014, Vol.34 (4), pp.1101-1108DOAJ
摘要:Background/Aims: The fatty acid profile in plasma lipids contributes to the increase of plasma high sensitivity C-reactive protein (hsCRP), a marker of inflammation and predictor of cardiovascular risk. The aim of this study was to examine the relationship between specific f...
作者:Tomasz Sledzinski , Justyna Korczynska ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2013, Vol.32 (2), pp.300-309DOAJ
摘要:Background/Aims: Cytosolic glycerol 3-phosphate dehydrogenase (cGPDH) is a key enzyme providing glycerol 3-phosphate for triacylglycerol synthesis in adipose tissue and is regarded as a marker for adipocyte differentiation. The aim of this study was to test the hypothesis th...
作者:Tomasz Sledzinski , Ryszard T. Smolenski
来源:[J].Journal of Steroid Biochemistry and Molecular Biology(IF 3.984), 2014, Vol.140, pp.63-70Elsevier
摘要:Abstract(#br)ZAC1 is a zinc-finger protein transcription factor, a transcriptional cofactor for nuclear receptors, and a co-activator of nuclear receptors, which interacts with multiple signaling pathways affecting apoptosis, cell cycle arrest, and metabolism. Some data sugg...

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