全部文献期刊会议图书|学者科研项目
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作者:Tim Holland-Letz , Frederik L. Giesel ...
来源:[J].European Journal of Nuclear Medicine and Molecular Imaging(IF 5.114), 2017, Vol.44 (8), pp.1258-1268
摘要:Since the clinical introduction of 68Ga-PSMA-11 PET/CT, this imaging method has rapidly spread and is now regarded as a significant step forward in the diagnosis of recurrent prostate cancer (PCa). The aim of this study was to analyse the influence of several variables...
作者:Tim Holland-Letz , John Babich
来源:[J].European Journal of Nuclear Medicine and Molecular Imaging(IF 5.114), 2017, Vol.44 (6), pp.950-959
摘要:Prostate-specific membrane antigen (PSMA)-targeting radioligand therapy (RLT) was introduced in 2011. The first report described the antitumor and side effects of a single dose. The aim of this analysis was to evaluate toxicity and antitumor activity after single and repetitive t...
作者:Tim Holland-Letz , Petra Schrotz-King ...
来源:[J].European Journal of Cancer(IF 5.061), 2020, Vol.127, pp.30-40
摘要:Abstract(#br)Blood-based protein biomarker signatures might be an alternative or supplement to existing methods for early detection of colorectal cancer (CRC) for population-based screening. The objective of this study was to derive a protein biomarker signature for early de...
作者:Tim Holland-Letz , Marc S. Raab ...
来源:[J].Cell Reports, 2017, Vol.20 (8), pp.1906-1920
摘要:Summary(#br)Chromosomal instability is a hallmark of cancer and correlates with the presence of extra centrosomes, which originate from centriole overduplication. Overduplicated centrioles lead to the formation of centriole rosettes, which mature into supernumerary centrosomes in...
作者:Tim Holland-Letz , Bastian Schilling ...
来源:[J].European Journal of Cancer(IF 5.061), 2019, Vol.119, pp.57-65
摘要:Abstract(#br)Background(#br)Recently, convolutional neural networks (CNNs) systematically outperformed dermatologists in distinguishing dermoscopic melanoma and nevi images. However, such a binary classification does not reflect the clinical reality of skin cancer screenings...
作者:Tim Holland-Letz , Christof von Kalle ...
来源:[J].European Journal of Cancer(IF 5.061), 2019, Vol.119, pp.11-17
摘要:Abstract(#br)Background(#br)Melanoma is the most dangerous type of skin cancer but is curable if detected early. Recent publications demonstrated that artificial intelligence is capable in classifying images of benign nevi and melanoma with dermatologist-level precision. How...
作者:Tim Holland-Letz , Jochen S. Utikal ...
来源:[J].European Journal of Cancer(IF 5.061), 2019, Vol.113, pp.47-54
摘要:Abstract(#br)Background(#br)Recent studies have successfully demonstrated the use of deep-learning algorithms for dermatologist-level classification of suspicious lesions by the use of excessive proprietary image databases and limited numbers of dermatologists. For the first...
作者:Tim Holland-Letz , Benjamin Izar ...
来源:[J].European Journal of Cancer(IF 5.061), 2019, Vol.120, pp.114-121
摘要:Abstract(#br)Background(#br)In recent studies, convolutional neural networks (CNNs) outperformed dermatologists in distinguishing dermoscopic images of melanoma and nevi. In these studies, dermatologists and artificial intelligence were considered as opponents. However, the combi...

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