全部文献期刊会议图书|学者科研项目
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作者:... Guido Sauter , Waldemar Wilczak , Till S. Clauditz
来源:[J].Urologic Oncology: Seminars and Original Investigations(IF 3.647), 2020, Vol.38 (2), pp.43.e13-43.e20
摘要:Abstract(#br)Background and methods(#br)8p deletions are common in renal cell carcinoma. To study their prognostic impact and association with kidney cancer phenotype, a tissue microarray with 1,809 cancers was analyzed by fluorescence in situ hybridization for 8p21 copy numbers....
作者:Till S. Clauditz , Andreas M. Luebke ...
来源:[J].Neoplasia, 2017, Vol.19 (9), pp.707-715
摘要:Abstract(#br)Biglycan (BGN), a proteoglycan of the extracellular matrix, is included in mRNA signatures for prostate cancer aggressiveness. To understand the impact of BGN on prognosis and its relationship to molecularly defined subsets, we analyzed BGN expression by immunohistoc...
作者:Till S. Clauditz , Tobias Hoenig ...
来源:[J].Experimental and Molecular Pathology(IF 2.128), 2013, Vol.94 (1), pp.155-159
摘要:Abstract(#br)Background(#br)Several lines of evidence indicate that mutational activation of KRAS is an early event in the carcinogenesis of non-small cell lung cancer (NSCLC). Nonetheless, previous studies report high frequencies of divergent KRAS mutational status between ...
作者:Till S. Clauditz , Djordje Atanackovic ...
来源:[J].Lung Cancer(IF 3.392), 2013, Vol.79 (3), pp.221-227
摘要:Abstract(#br)Next to EGFR mutation, EGFR gene copy number evaluated by fluorescence in situ hybridization (FISH) emerged as a potential predictive marker for sensitivity to EGFR tyrosine kinase inhibitors, although controversial data exist. As the diagnostic accuracy of predictiv...
作者:Till S. Clauditz , Ronald Simon ...
来源:[J].Disease Markers(IF 2.14), 2019, Vol.2019
摘要:Syndecan-1 (CD138) is a transmembrane proteoglycan known to be expressed in various normal and malignant tissues. It is of interest because of a possible prognostic role of differential expression in tumors and its role as a target for indatuximab, a monoclonal antibody coupled w...
作者:Till S. Clauditz , Carsten Bokemeyer ...
来源:[J].Genes, Chromosomes and Cancer(IF 3.546), 2014, Vol.53 (3), pp.228-239
摘要:In cancer therapy, the number of drugs targeting cells with characteristic molecular aberrations is continuously rising. However, application of these new drugs still is limited to a few tumor entities. The aim of this study was to test the concept of routinely identifying a...
作者:... Kerstin Borgmann , Adrian Muenscher , Till S. Clauditz
来源:[J].International Journal of Cancer(IF 6.198), 2014, Vol.135 (5), pp.1142-1152
摘要:The prognosis of head and neck squamous cell carcinoma (HNSCC) patients remains poor. The identification of high‐risk subgroups is needed for the development of custom‐tailored therapies. The expression of cancer‐testis antigens (CTAs) has been linked to a worse prognos...
作者:Till S. Clauditz , Michelle Moore ...
来源:[J].Diagnostic Histopathology, 2020, Vol.26 (1), pp.39-46
摘要:Abstract(#br)Although the majority of gastric carcinomas are sporadic neoplasms, approximately 10% show familial aggregation, and a hereditary cause is determined in 1–3% cases. Of these, hereditary diffuse gastric cancer (HDGC) is the most recognized predisposition syndrome...

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