全部文献期刊会议图书|学者科研项目
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作者:Till Krech , Florian Ewald ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)
摘要:Hepatocellular carcinoma has a dismal prognosis due to recurrence rates of up to 70% after curative resection. Early recurrence is driven by synchronous microscopic intrahepatic metastases. The predictive value of histological parameters is discussed controversially and adjuvant ...
作者:Till Krech , Maximilian Dämmrich ...
来源:[J].Pathology - Research and Practice(IF 1.213), 2019, Vol.215 (11)
摘要:Abstract(#br)Lobular neoplasia (LN), invasive lobular breast cancer (ILBC) and related pleomorphic variants represent a distinct group of neoplastic mammary gland lesions. This study assessed the inter-observer agreement of histological grading in a series of ILBC and LN.(#b...
作者:Till Krech , Roman Zenouzi ...
来源:[J].Journal of Hepatology(IF 9.858), 2018, Vol.68 (4), pp.754-763
摘要:Background & Aims(#br)Liver fibrosis regression but also progression may occur in patients with autoimmune hepatitis (AIH) under treatment. There is a need for non-invasive surrogate markers for fibrosis development in AIH to better guide immunosuppressive treatment. The aim...
作者:Till Krech , Till Clauditz ...
来源:[J].Neoplasia, 2017, Vol.19 (4), pp.279-287
摘要:Abstract(#br)The A Disintegrin and Metalloproteinase (ADAM) family of endopeptidases plays a role in many solid cancers and includes promising targets for anticancer therapies. Deregulation of ADAM15 has been linked to tumor aggressiveness and cell line studies suggest that ADAM1...
作者:Till Krech , Khalil Karimi ...
来源:[J].Scientific Reports(IF 2.927), 2018, Vol.8 (1), pp.1-11
摘要:Abstract Multi drug resistance protein 2 knockout mice (Mdr2 −/− are a mouse model of chronic liver inflammation and inflammation-induced tumour development. Here we investigated the kinetics of early heme oxygenase 1 (HO-1 induction on inflammation, tumour development, and ...
作者:Till Krech , Daphne DeTemple ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (7)
摘要:Being an integral part of basic, translational and clinical research, the demand for primary human hepatocytes (PHH) is continuously growing while the availability of tissue resection material for the isolation of metabolically competent PHH remains limited. To overcome curr...
作者:Till Krech , Christina Weiler-Normann ...
来源:[J].Frontiers in Immunology, 2019, Vol.10
摘要:Background: Natural Killer T (NKT) cells are CD1d-restricted innate-like T cells that can rapidly release stored cytokines upon recognition of lipid antigens. In mice, type I NKT cells seem to promote liver inflammation, whereas type II NKT cells seem to restrict hepatitis. ...
作者:Till Krech , Ralf Lichtinghagen ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.12 (6)
摘要:Autoimmune hepatitis (AIH) is a chronic hepatitis with an increasing incidence. The majority of patients require life-long immunosuppression and incomplete treatment response is associated with a disease progression. An abnormal iron homeostasis or hyperferritinemia is associated...

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