全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Constantinos Koumenis , Thomas J. Goodwin , Melpo Christofidou-Solomidou
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2016, Vol.17 (6)DOAJ
摘要:Spaceflight occasionally requires multiple extravehicular activities (EVA) that potentially subject astronauts to repeated changes in ambient oxygen superimposed on those of space radiation exposure. We thus developed a novel in vitro model system to test lung cell damage fo...
作者:Michael A. Schmidt , Thomas J. Goodwin , Ralph Pelligra
来源:[J].Metabolomics(IF 4.433), 2016, Vol.12 (2)Springer
摘要:Abstract(#br)The next major steps in human spaceflight include flyby, orbital, and landing missions to the Moon, Mars, and near earth asteroids. The first crewed deep space mission is expected to launch in 2022, which affords less than 7 years to address the complex question of w...
作者:Michael A. Schmidt , Thomas J. Goodwin
来源:[J].Metabolomics(IF 4.433), 2013, Vol.9 (6), pp.1134-1156Springer
摘要:Abstract(#br)Space flight is one of the most extreme conditions encountered by humans. Advances in Omics methodologies (genomics, transcriptomics, proteomics, and metabolomics) have revealed that unique differences exist between individuals. These differences can be amplifie...
作者:Thomas J. Goodwin , Maureen McCarthy ...
来源:[J].Methods(IF 3.641), 2015, Vol.90, pp.76-84Elsevier
摘要:Abstract(#br)Virus–host cell interactions are most commonly analyzed in cells maintained in vitro as two-dimensional tissue cultures. However, these in vitro conditions vary quite drastically from the tissues that are commonly infected in vivo . Over the years, a number of s...
作者:Thomas J. Goodwin , J. Stephen Alexander ...
来源:[J].Microbes and Infection(IF 2.92), 2006, Vol.8 (7), pp.1813-1825Elsevier
摘要:Abstract(#br)In vitro cell culture models used to study how Salmonella initiates disease at the intestinal epithelium would benefit from the recognition that organs and tissues function in a three-dimensional (3-D) environment and that this spatial context is necessary for develo...
作者:Thomas J. Goodwin , Tacey L. Prewett ...
来源:[J].In Vitro Cellular & Developmental Biology - Animal(IF 1.289), 1997, Vol.33 (5), pp.366-374Springer
摘要:Summary(#br)The Rotating-Wall Vessel (RWV) is a novel in vitro cell culture system used to successfully culture a cell line derived from a heterologous mixed mullerian tumor cell of the ovary. Although the original tumor was comprised of both epithelial and mesodermal components,...
作者:... Dawn M. Wankowski , Brian R. Unsworth , Thomas J. Goodwin
来源:[J].In Vitro Cellular & Developmental Biology - Animal(IF 1.289), 1997, Vol.33 (5), pp.344-351Springer
摘要:Summary(#br)The aim of this study was to test the versatility of a new basal cell culture medium, GTSF-2. In addition to traditional growth-factors, GTSF-2 contains a blend of three sugars (glucose, galactose, and fructose) at their physiological levels. For these studies, we iso...
作者:Thomas J. Goodwin , Shi-Ming Chang ...
来源:[J].In Vitro Cellular & Developmental Biology - Animal(IF 1.289), 1997, Vol.33 (5), pp.375-380Springer
摘要:Summary(#br)A novel in vitro human prostate cancer model was established by using a coculture technique in which isolated human prostate fibroblasts were observed to grow as a mixed culture with isolated human prostate cancer cells (LNCaP) on microcarrier beads under microgravity...

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