全部文献期刊会议图书|学者科研项目
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作者:Thomas Michael , Yang Luobin ...
来源:[J].BMC Genomics(IF 4.397), 2011, Vol.12 (1), pp.66DOAJ
摘要:Abstract Background Methods for gene-class testing, such as Gene Set Enrichment Analysis (GSEA), incorporate biological knowledge into the analysis and interpretation of microarray data by comparing gene expression patterns to pathways, systems and emergent phenotypes. However, t...
作者:Thomas Michael , Sheran Jane ...
来源:[J].BMC Pulmonary Medicine(IF 2.76), 2007, Vol.7 (1), pp.4DOAJ
摘要:Abstract Background Despite effective treatments, asthma outcomes remain suboptimal. Interest exists in complementary therapies, particularly in herbal remedies for asthma treatment, currently with inconclusive evidence of efficacy. The encapsulated botanical mixture AKL1 ha...
作者:Metzger Kelsey , Thomas Michael
来源:[J].BMC Evolutionary Biology(IF 3.285), 2010, Vol.10 (1), pp.139DOAJ
摘要:Abstract Background CC chemokine receptor proteins (CCR1 through CCR10) are seven-transmembrane G-protein coupled receptors whose signaling pathways are known for their important roles coordinating immune system responses through targeted trafficking of white blood cells. In...
作者:Johnson Deborah , Hill Jeffrey , Thomas Michael
来源:[J].BMC Evolutionary Biology(IF 3.285), 2006, Vol.6 (1), pp.64DOAJ
摘要:Abstract Background In plants, tandem, segmental and whole-genome duplications are prevalent, resulting in large numbers of duplicate loci. Recent studies suggest that duplicate genes diverge predominantly through the partitioning of expression and that breadth of gene expression...
作者:Kreuter Michael , Vansteenkiste Johan ...
来源:[J].BMC Cancer(IF 3.333), 2007, Vol.7 (1), pp.77DOAJ
摘要:Abstract Background Adjuvant chemotherapy has been proven to be beneficial for patients with early stage non-small cell lung cancer. However, toxicity and insufficient dose delivery have been critical issues with the chemotherapy used. Doublet regimens with pemetrexed, a multi-ta...
作者:... Hurst John R , Thomas Michael , Wedzicha Jadwiga A
来源:[J].BMC Pulmonary Medicine(IF 2.76), 2012, Vol.12 (1)DOAJ
摘要:Abstract Background 25-hydroxyvitamin D deficiency is associated with COPD and increased susceptibility to infection in the general population. Methods We investigated whether COPD patients deficient in 25-hydroxyvitamin D were more likely to be frequent exacerbators, had re...
作者:Kreuter Michael , De Leyn Paul
来源:[J].BMC Cancer(IF 3.333), 2007, Vol.7 (1)DOAJ
摘要:Abstract Background Adjuvant chemotherapy has been proven to be beneficial for patients with early stage non-small cell lung cancer. However, toxicity and insufficient dose delivery have been critical issues with the chemotherapy used. Doublet regimens with pemetrexed, a multi-ta...
作者:Thomas Michael , Zhang WenRu ...
来源:[J].Journal of Neuroinflammation(IF 4.351), 2005, Vol.2 (1), pp.19DOAJ
摘要:Abstract Background Inflammation and oxidative stress play a critical role in neurodegeneration associated with acute and chronic insults of the nervous system. Notably, affected neurons are often responsive to and dependent on trophic factors such as nerve growth factor (NG...

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