全部文献期刊会议图书|学者科研项目
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作者:... Jesse Aaron , Teng-Leong Chew , Timothy A. Springer
来源:[J].Cell Reports, 2018, Vol.22 (7), pp.1903-1912
摘要:Summary(#br)We use super-resolution interferometric photoactivation and localization microscopy (iPALM) and a constrained photoactivatable fluorescent protein integrin fusion to measure the displacement of the head of integrin lymphocyte function-associated 1 (LFA-1) resulting fr...
作者:Teng-Leong Chew , Eric Betzig ...
来源:[J].Cell Reports, 2019, Vol.26 (12), pp.3369-3379.e5
摘要:Summary: Cytoskeletal actin dynamics is essential for T cell activation. Here, we show evidence that the binding kinetics of the antigen engaging the T cell receptor influences the nanoscale actin organization and mechanics of the immune synapse. Using an engineered T cell system...
作者:... Jesse Aaron , Teng-Leong Chew , Timothy A. Springer
来源:[J].Cell Reports, 2018, Vol.22 (7), pp.1903-1912
摘要:We use super-resolution interferometric photoactivation and localization microscopy (iPALM) and a constrained photoactivatable fluorescent protein integrin fusion to measure the displacement of the head of integrin lymphocyte function-associated 1 (LFA-1) resulting from integrin ...
作者:John M. Heddleston , Teng-Leong Chew
来源:[J].International Journal of Biochemistry and Cell Biology(IF 4.152), 2016, Vol.80, pp.119-123
摘要:Abstract(#br)Capturing dynamic processes in live samples is a nontrivial task in biological imaging. Although fluorescence provides high specificity and contrast compared to other light microscopy techniques, the photophysical principles of this method can have a harmful effect o...
作者:Teng-Leong Chew , Samuel A. Safran ...
来源:[J].Nature Cell Biology(IF 20.761), 2017, Vol.19 (3), pp.258-258
摘要:Nature Cell Biology 19, 133–141 (2017); published online 23 January 2017; corrected after print 31 January 2017 In the version of this Letter originally published, the numbering of Supplementary Video files and the references to those files in the text did not match. All onl...
作者:Teng-Leong Chew , Samuel A. Safran ...
来源:[J].Nature Cell Biology(IF 20.761), 2017, Vol.19 (2), pp.133-141
摘要:Using structured illumination microscopy, Beach et al. and Hu et al. visualize the assembly of myosin II filaments in cells, describing a filament-partitioning mechanism, and long-range self-organization of filaments, respectively.(#br)Abstract(#br)Although myosin II filamen...
作者:Teng-Leong Chew , Fuminori Sato ...
来源:[J].Disease Models & Mechanisms, 2015, Vol.8 (6), pp.553-564
摘要:Neural damage is a devastating outcome of physical trauma. The glia are one of the main effectors of neuronal repair in the nervous system, but the dynamic interactions between peripheral neurons and Schwann cells during injury and regeneration remain incompletely characteri...

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