全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Sylvie Rottey , Karel Decaestecker ...
来源:[J].Journal of Translational Medicine(IF 3.459), 2017, Vol.15 (1)Springer
摘要:Current first-line standard of therapy for metastatic urothelial carcinoma is platinum-based combination chemotherapy. Pembrolizumab in phase III has demonstrated a promising overall response rate of 21.1% in patients with progression or recurrence after platinum-based chemothera...
作者:Sylvie Rottey , Karim Vermaelen ...
来源:[J].Radiation Oncology(IF 2.107), 2017, Vol.12 (1)Springer
摘要:The primary objective was to determine maximum tolerated radiation dose in patients with metastatic renal cell carcinoma on pazopanib treatment.
作者:... Katrien Vandecasteele , Sylvie Rottey , Liesbeth Ferdinande
来源:[J].Head and Neck Pathology, 2017, Vol.11 (3), pp.354-363Springer
摘要:The assessment of tumor infiltrating lymphocytes (TILs) has recently emerged as a prognostic biomarker in several solid tumors. Quantification and subtyping of TILs reflects the immune response in the tumor microenvironment, contributing to either tumoral immune attack or escape ...
作者:Sylvie Rottey , Yolande Lievens ...
来源:[J].BMC Cancer(IF 3.333), 2015, Vol.15 (1)Springer
摘要:Abstract(#br) Background(#br)Evidence-based guidelines concerning the older head and neck cancer (HNCA) patient are lacking. Accurate patient selection for optimal care management is therefore challenging. We examined if geriatric assessment is indicative of long-term health...
作者:Sylvie Rottey , Tom Vercauteren ...
来源:[J].Strahlentherapie und Onkologie(IF 4.163), 2018, Vol.194 (8), pp.727-736Springer
摘要:Abstract(#br) Purpose(#br)To evaluate feasibility, disease control, survival, and toxicity after adaptive 18 F-fluorodeoxyglucose (FDG) positron emisson tomography (PET) guided radiotherapy in patients with recurrent and second primary head and neck squamous cell carcinoma.(...
作者:Sylvie Rottey , Marleen Praet ...
来源:[J].Clinical Genitourinary Cancer(IF 1.429), 2014, Vol.12 (3), pp.160-166Elsevier
摘要:Abstract(#br)Introduction(#br)The objectives of this study were to assess the agreement of GS on biopsy compared with RP specimens and to assess whether an increased number of biopsy cylinders and the 2005 International Society of Urological Pathology (ISUP) GS modification ...
作者:Sylvie Rottey , Karin Leunen ...
来源:[J].Clinical Therapeutics(IF 2.23), 2016, Vol.38 (10), pp.2286-2299Elsevier
摘要:Abstract(#br)Purpose(#br)The metabolism of olaparib, a potent inhibitor of poly(ADP-ribose) polymerase (PARP) with demonstrated efficacy in patients with BRCA -mutated ovarian cancer, is mediated by cytochrome P450 (CYP) enzymes (predominantly CYP3A4/5). We assessed the pote...
作者:Sylvie Rottey , Betrand Tombal ...
来源:[J].European Urology(IF 10.476), 2019, Vol.76 (4), pp.437-440Elsevier
摘要:Abstract(#br)The European Organisation for Research and Treatment of Cancer SURTIME trial explored timing of sunitinib, a tyrosine kinase inhibitor (TKI), and cytoreductive nephrectomy (CN) in patients with metastatic renal cell carcinoma. Previous retrospective studies sugg...
作者:Sylvie Rottey , Jill Geenen ...
来源:[J].The Lancet Oncology(IF 25.117), 2019, Vol.20 (8), pp.1124-1135Elsevier
摘要:Summary(#br)Background(#br)Trastuzumab duocarmazine is a novel HER2-targeting antibody–drug conjugate comprised of trastuzumab covalently bound to a linker drug containing duocarmycin. Preclinical studies showed promising antitumour activity in various models. In this first-...

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