全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Svetoslav Slavov , Iva Stoyanova-Slavova ...
来源:[J].Archives of Toxicology(IF 5.215), 2017, Vol.91 (12), pp.3885-3895Springer
摘要:Recent reports have noted that a number of compounds that block the human Ether-à-go-go related gene (hERG) ion channel also induce phospholipidosis (PLD). To explore a hypothesis explaining why most PLD inducers are also hERG inhibitors, a modeling approach was undertaken w...
作者:Svetoslav Slavov , Fernanda Ferreira ...
来源:[J].Journal of Vector Borne Diseases(IF 1.041), 2019, Vol.56 (2), pp.166-169Wolters Kluwer
摘要:During zika and dengue viruse (ZIKV and DENV) outbreaks, the majority of the infected individuals remain clinically asymptomatic. Such asymptomatic individuals may occasionally acquire both arboviruses, donate blood, and contaminate haemoderivatives. The aim of this study wa...
作者:Svetoslav Slavov , Kelly Davis ...
来源:[J].Metabolomics(IF 4.433), 2014, Vol.10 (6), pp.1293-1304Springer
摘要:Abstract(#br)Understanding mechanisms of liver injury can enable better preclinical testing and clinical management of patients. Carbon tetrachloride (CCl 4 ), used extensively as a model hepatotoxicant, induces lipid perturbation and increases in plasma bile acids (BAs). An...
作者:Svetoslav Slavov , Pierre Alusta ...
来源:[J].Journal of Analytical and Applied Pyrolysis(IF 2.56), 2017, Vol.124, pp.393-402Elsevier
摘要:Abstract(#br)Algorithms applied to mass spectra of Salmonella isolates were used to achieve accurate and rapid serotyping. Two classification strategies were developed, one using all ions and the other, only 19. Without feature selection, classification based on all ions ( m...
作者:Svetoslav Slavov , Pierre Alusta ...
来源:[J].Journal of Analytical and Applied Pyrolysis(IF 2.56), 2016Elsevier
摘要:Abstract(#br)Algorithms applied to mass spectra of Salmonella isolates were used to achieve accurate and rapid serotyping. Two classification strategies were developed, one using all ions and the other, only 19. Without feature selection, classification based on all ions ( m...
作者:Svetoslav Slavov , Giuseppina Gini , Emilio Benfenati
来源:[J].Journal of Environmental Science and Health, Part B(IF 1.211), 2008, Vol.43 (8), pp.633-637Taylor & Francis
摘要:The pesticides originally designed to kill target organisms are dangerous for many other wild species. Since they are applied directly to the environment, they can easily reach the water basins and the topsoil. A dataset of 125 aromatic pesticides with well-expressed aquatic toxi...
作者:Svetoslav Slavov , Maksim Radzvilovits ...
来源:[J].Water Research(IF 4.655), 2010, Vol.44 (8), pp.2451-2460Elsevier
摘要:Abstract(#br)The experimental log EC 50 toxicity values of 104 compounds causing bioluminescent repression of the bacterium strain Pseudomonas isolated from an industrial wastewater were studied. Using the Best Multilinear Regression method implemented in CODESSA PRO, models...
作者:Svetoslav Slavov , Dimitar A. Dobchev ...
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2006, Vol.14 (14), pp.4888-4917Elsevier
摘要:Abstract(#br)Experimental blood–brain partition coefficients (log BB) for a diverse set of 113 drug molecules are correlated with computed structural descriptors using CODESSA-PRO and ISIDA programs to give statistically significant QSAR models based respectively, on molecul...
作者:Svetoslav Slavov , Laura K. Schnackenberg ...
来源:[J].Computational and Structural Biotechnology Journal, 2014, Vol.10 (17), pp.78-89Elsevier
摘要:Abstract(#br)It has been estimated that 10% of acute liver failure is due to “idiosyncratic hepatotoxicity”. The inability to identify such compounds with classical preclinical markers of hepatotoxicity has driven the need to discover a mechanism-based biomarker panel for he...
作者:Svetoslav Slavov , Dimitar A. Dobchev
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2006, Vol.14 (22), pp.7490-7500Elsevier
摘要:Abstract(#br)A QSAR methodology that involves multilinear (Hansch-type) and nonlinear (ANN backpropagation) approaches was developed to correlate the antiplatelet activity of 60 benzoxazinone derivatives against factor Xa. The statistical characteristics provided by multilinear m...

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