全部文献期刊会议图书|学者科研项目
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作者:... Alexandru Neagu , Sven Ove Ögren , Catharina Lavebratt
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (11)DOAJ
摘要:Pregnant women with epilepsy have to balance maternal and fetal risks associated with uncontrolled seizures against the potential teratogenic effects from antiepileptic drugs (AEDs). Carbamazepine (CBZ) is among the four most commonly used AEDs for treatment of pregnant epileptic...
作者:... Johan Sandin , Lars Terenius , Sven Ove Ögren
来源:[J].European Neuropsychopharmacology(IF 4.595), 2017, Vol.27 (12), pp.1298-1307Elsevier
摘要:Abstract(#br)The endogenous neuropeptide nociceptin (N/OFQ), which mediates its actions via the nociceptin receptor (NOP), is implicated in multiple behavioural and physiological functions. This study examined the effects of the NOP agonists N/OFQ and the synthetic agonist R...
作者:... Krister Kristensson , Sven Ove Ögren , Håkan Karlsson
来源:[J].Brain Behavior and Immunity(IF 5.612), 2009, Vol.23 (6), pp.733-741Elsevier
摘要:Abstract(#br)Epidemiological studies suggest that early life infections may contribute to the development of psychiatric disorders characterized by cognitive deficits. Here, we studied the effects of a neonatal influenza A/WSN/33 virus infection on locomotor activity, workin...
作者:... Sarah Holst , Gilberto Fisone , Sven Ove Ögren
来源:[J].European Neuropsychopharmacology(IF 4.595), 2019, Vol.29 (5), pp.616-628Elsevier
摘要:Abstract(#br)Schizophrenia is associated with cognitive impairments related to hypofunction in glutamatergic N-methyl- D -aspartate receptor (NMDAR) transmission. Phencyclidine (PCP), a non-competitive NMDAR antagonist, models schizophrenia-like behavioral symptoms including cogn...
作者:Sven Ove Ögren , Marie Vahter ...
来源:[J].Toxicology(IF 4.017), 2007, Vol.241 (3), pp.119-133Elsevier
摘要:Abstract(#br)Adenosine and its receptors are, as part of the brain stress response, potential targets for neuroprotective drugs. We have investigated if the adenosine receptor system affects the developmental neurotoxicity caused by the fish pollutant methylmercury (MeHg). B...
作者:Sven Ove Ögren , Kjell Fuxe
来源:[J].European Neuropsychopharmacology(IF 4.595), 2016, Vol.26 (3), pp.467-476Elsevier
摘要:Abstract(#br)Newer, “atypical” antipsychotics carry a lower risk of motor side-effects than older, “typical” compounds. It has been proposed that a ~100-fold faster dissociation from the dopamine D 2 receptor (D 2 R) distinguishes atypical from typical antipsychotics. F...
作者:... Guy M. Goodwin , Andreas Meyer-Lindenberg , Sven Ove Ögren
来源:[J].European Neuropsychopharmacology(IF 4.595), 2015, Vol.25 (5), pp.599-656Elsevier
摘要:Abstract(#br)Modern neuropsychopharmacology commenced in the 1950s with the serendipitous discovery of first-generation antipsychotics and antidepressants which were therapeutically effective yet had marked adverse effects. Today, a broader palette of safer and better-tolerated a...
作者:... M. Hamon , Andreas Meyer-Lindenberg , Sven Ove Ögren
来源:[J].European Neuropsychopharmacology(IF 4.595), 2015, Vol.25 (5), pp.591-598Elsevier
摘要:Abstract(#br)Pharmacotherapy is effective in helping many patients suffering from psychiatric and neurological disorders, and both psychotherapeutic and stimulation-based techniques likewise have important roles to play in their treatment. However, therapeutic progress has r...
作者:Sven Ove Ögren , Haleh Razani ...
来源:[J].Physiology & Behavior(IF 3.16), 2007, Vol.92 (1), pp.172-179Elsevier
摘要:Abstract(#br)The neuropeptide galanin is widely distributed throughout the central nervous system with multiple and diverse biological functions mediated by different receptor subtypes. In the rat, galanin-like immunoreactivity is expressed in a population of 5-hydroxytryptamine ...
作者:Sven Ove Ögren , Pär A Schött ...
来源:[J].Brain Research(IF 2.879), 1999, Vol.848 (1-2), pp.174-182Elsevier
摘要:Abstract(#br)A number of studies indicate that galanin (GAL) is a potent modulator of basal acetylcholine release in the rat forebrain e.g. in the cholinergic neurons of the septo-hippocampal projections. Thus, GAL perfused through the microdialysis probe decreased basal acetylch...

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