全部文献期刊会议图书|学者科研项目
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作者:Susanna Molas , Andrew R. Tapper ...
来源:[J].Scientific Reports(IF 2.927), 2020, Vol.10 (Pt B), pp.1905-1926
摘要:Abstract(#br)Tobacco use is the leading preventable cause of mortality in the world. The limited number of smoking cessation aids currently available are minimally effective, highlighting the need for novel therapeutic interventions. We describe a genome-wide approach to identify...
作者:Susanna Molas , Steven DeGroot ...
来源:[J].Trends in Pharmacological Sciences(IF 9.25), 2016
摘要:While innovative modern neuroscience approaches have aided in discerning brain circuitry underlying negative emotional behaviors including fear and anxiety responses, how these circuits are recruited in normal and pathological conditions remains poorly understood. Recently, ...
作者:Susanna Molas , Rubing Zhao-Shea ...
来源:[J].Nature Neuroscience(IF 15.251), 2017, Vol.20 (9), pp.1260-1268
摘要:The mechanistic basis of how novel stimuli become familiar with repeated exposures has remained elusive. Molas et al . demonstrate that familiarity activates the interpeduncular nucleus, thereby reducing motivation to explore. Familiarity signaling in the interpeduncular nucleus ...
作者:Susanna Molas , Mara Dierssen
来源:[J].Neuroscience and Biobehavioral Reviews(IF 9.44), 2014, Vol.46, pp.315-325
摘要:Abstract(#br)The involvement of the cholinergic system in learning, memory and attention has long been recognized, although its neurobiological mechanisms are not fully understood. Recent evidence identifies the endogenous cholinergic signaling via nicotinic acetylcholine re...
作者:Susanna Molas , Xavier Gallego ...
来源:[J].Drug and Alcohol Dependence(IF 3.141), 2012, Vol.122 (3), pp.247-252
摘要:Abstract(#br)Recent studies have revealed that sequence variants in genes encoding the α3/α5/β4 nicotinic acetylcholine receptor subunits are associated with nicotine dependence. In this study, we evaluated two specific aspects of executive functioning related to drug addict...
作者:Susanna Molas , Noemí Robles ...
来源:[J].Alcohol(IF 2.255), 2012, Vol.46 (3), pp.205-215
摘要:Abstract(#br)Abuse of alcohol and smoking are extensively co-morbid. Some studies suggest partial commonality of action of alcohol and nicotine mediated through nicotinic acetylcholine receptors (nAChRs). We tested mice with transgenic over expression of the alpha 5, alpha 3, bet...
作者:Susanna Molas , Alejandro Amador-Arjona ...
来源:[J].Amino Acids(IF 3.914), 2012, Vol.43 (2), pp.897-909
摘要:Abstract(#br)Nicotinic acetylcholine receptors (nAChRs) are ligand-gated pentameric ion channels that account for the effects of nicotine. Recent genetic studies have highlighted the importance of variants of the CHRNA5/A3/B4 genomic cluster in human nicotine dependence. Amo...

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