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作者:Surash Ramanathan , Suhanya Parthasarathy ...
来源:[J].Molecules(IF 2.428), 2015, Vol.20 (3), pp.4915-4927DOAJ
摘要:Varied pharmacological responses have been reported for mitragynine in the literature, but no supportive scientific explanations have been given for this. These studies have been undertaken without a sufficient understanding of the physicochemical properties of mitragynine. ...
作者:... Sabariah Ismail , Surash Ramanathan , Mun Fei Yam
来源:[J].Molecules(IF 2.428), 2010, Vol.15 (4), pp.2925DOAJ
摘要:Ethanolic extract of Curcuma xanthorrhiza was used to evaluate the analgesic and toxicity effects in vivo. The extract was standardized using GC-MS, which showed that 1 mg of Curcuma xanthorrhiza ethanolic extract contains 0.1238 mg of xanthorrhizol. The analgesic activity w...
作者:Surash Ramanathan , Sabariah Ismail ...
来源:[J].Molecules(IF 2.428), 2009, Vol.14 (10), pp.3964DOAJ
摘要:Studies on the antioxidant and antimicrobial activities of Mitragyna speciosa leaf extracts are lacking. In this study the antioxidant properties of water, methanolic and alkaloid M. speciosa leaf extracts were evaluated using the DPPH (2,2-diphenyl-1- picrylhydrazyl) radica...
作者:Surash Ramanathan , Sreenivasan Sasidharan ...
来源:[J].Molecules(IF 2.428), 2009, Vol.14 (11), pp.4476DOAJ
摘要:This study examines the in vitro antioxidant activities of the methanol extract of Swietenia mahagoni seeds (SMCM seed extract). The extract was screened for possible antioxidant activities by free radical scavenging activity (DPPH), xanthine oxidase inhibition (XOI), hydrog...
作者:Surash Ramanathan , Mohd Ikram Mohd Said
来源:[J].Molecules(IF 2.428), 2010, Vol.15 (1), pp.432DOAJ
摘要:In the present study, we investigate the effects of three different Mitragyna speciosa extracts, namely methanolic, aqueous and total alkaloid extracts, on glutathione transferase-specific activity in male Sprague Dawley rat liver cytosol in vitro and in vivo. In the in vitr...
作者:Surash Ramanathan , Sreenivasan Sasidharan
来源:[J].Indian Journal of Pharmacology(IF 0.583), 2014, Vol.46 (5), pp.515-520Wolters Kluwer
摘要:Aim: Clitoria ternatea Linn. (C. ternatea) is an Ayurvedic herb traditionally used as medicine to relieve inflammatory, rheumatism, ear diseases, fever, arthritis, eye ailments, sore throat and body ache. This study aims to evaluate and elucidate the possible mechanism under...
作者:... Sabariah Ismail , Surash Ramanathan , Mun Fei Yam
来源:[J].Molecules(IF 2.428), 2010, Vol.15 (4), pp.2925-2934DOAJ
摘要:Ethanolic extract of Curcuma xanthorrhiza was used to evaluate the analgesic and toxicity effects in vivo. The extract was standardized using GC-MS, which showed that 1 mg of Curcuma xanthorrhiza ethanolic extract contains 0.1238 mg of xanthorrhizol. The analgesic activity w...
作者:Surash Ramanathan , Mohd Nizam Mordi ...
来源:[J].Molecules(IF 2.428), 2010, Vol.15 (1), pp.432-441DOAJ
摘要:In the present study, we investigate the effects of three different Mitragyna speciosa extracts, namely methanolic, aqueous and total alkaloid extracts, on glutathione transferase-specific activity in male Sprague Dawley rat liver cytosol in vitro and in vivo. In the in vitr...
作者:Surash Ramanathan , Sabariah Ismail ...
来源:[J].Molecules(IF 2.428), 2009, Vol.14 (10), pp.3964-3974DOAJ
摘要:Studies on the antioxidant and antimicrobial activities of Mitragyna speciosa leaf extracts are lacking. In this study the antioxidant properties of water, methanolic and alkaloid M. speciosa leaf extracts were evaluated using the DPPH (2,2-diphenyl-1- picrylhydrazyl) radica...
作者:Surash Ramanathan , Suhanya Parthasarathy ...
来源:[J].The Journal of Physiological Sciences(IF 1.089), 2014, Vol.64 (3), pp.161-169Springer
摘要:Abstract(#br)The effects of mitragynine on anxiety-related behaviours in the open-field and elevated plus-maze tests were evaluated. Male Sprague–Dawley rats were orally treated with mitragynine (10, 20 and 40 mg/kg) or diazepam (10 mg/kg) 60 min before behavioural testing. ...

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