全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Tae Won Park , Jung Min Park , Sung Min Son
来源:[J].International Journal of Automotive Technology(IF 0.69), 2017, Vol.18 (6), pp.1027-1035Springer
摘要:In vehicle braking systems, the non-uniform contact pressure distribution on the brake pad is a major cause of uneven wear. The experimental approach of the wear phenomenon is the time consuming and costly. For this reason, a threedimensional finite element (FE) model of a brake ...
作者:Sun Wook Park , Sung Min Son , Na Kyung Lee
来源:[J].Neural Regeneration Research(IF 0.144), 2017, Vol.12 (5), pp.765-769DOAJ
摘要:This study aimed to investigate the effects of exercise-induced muscle fatigue in the unaffected knee joint on postural control and kinematic changes in stroke patients. Forty participants (20 stroke patients, 20 age-matched healthy participants) were recruited. To induce fatigue...
作者:Sung Min Son , Seokjo Kang ...
来源:[J].Molecular Neurodegeneration(IF 4.007), 2015, Vol.10 (1)Springer
摘要:Abstract(#br) Background(#br)Insulin degrading enzyme (IDE) is a major protease of amyloid beta peptide (Aβ), a prominent toxic protein in Alzheimer’s disease (AD) pathogenesis. Previous studies suggested that statins promote IDE secretion; however, the underlying mechanism ...
作者:Sung Min Son , Hyundong Song ...
来源:[J].Molecular Neurodegeneration(IF 4.007), 2016, Vol.11 (1)Springer
摘要:Abstract(#br) Background(#br)The receptor for advanced glycation end products (RAGE) has been found to interact with amyloid β (Aβ). Although RAGE does not have any kinase motifs in its cytosolic domain, the interaction between RAGE and Aβ triggers multiple cellular signalin...
作者:Sung Min Son , Dong Woo Nam ...
来源:[J].Neurobiology of Aging(IF 6.166), 2015, Vol.36 (12), pp.3214-3227Elsevier
摘要:Abstract(#br)Alzheimer's disease (AD) is characterized by impaired cognitive function and memory loss, which are often the result of synaptic pathology. Thrombospondin (TSP) is an astrocyte-secreted protein, well known for its function as a modulator of synaptogenesis and ne...
作者:Sung Min Son , Eun Sun Jung ...
来源:[J].Neurobiology of Aging(IF 6.166), 2012, Vol.33 (5), pp.1006.e11-1006.e23Elsevier
摘要:Abstract(#br)Pathological autophagic vacuoles (AVs) accumulate in the brains of Alzheimer's disease (AD) patients, but the mechanisms by which they are induced are unknown. In this study, we found that the formation of AVs was mediated by activation of adenosine monophosphat...
作者:Sung Min Son , Moon-Yong Cha ...
来源:[J].Autophagy(IF 12.042), 2016, Vol.12 (5), pp.784-800Taylor & Francis
摘要:ABSTRACT(#br)The secretion of proteins that lack a signal sequence to the extracellular milieu is regulated by their transition through the unconventional secretory pathway. IDE (insulin-degrading enzyme) is one of the major proteases of amyloid beta peptide (Aβ), a presumed...
作者:Sung Min Son , Yong Woo Kim ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2009, Vol.386 (1), pp.175-180Elsevier
摘要:Abstract(#br)The protease BACE1 (β-site APP-cleaving enzyme 1) is essential for the generation of amyloid beta (Aβ) from amyloid precursor protein (APP). Although BACE1 is expressed primarily in neurons, which are a principal source of Aβ in the brain, the mechanism that und...
作者:... Seokjo Kang , Sung Min Son , Inhee Mook‐Jung
来源:[J].Glia(IF 5.066), 2016, Vol.64 (12), pp.2274-2290Wiley
摘要:Pathological hallmarks of Alzheimer's disease (AD) include extracellularly accumulated amyloid β (Aβ) plaques and intracellular neurofibrillary tangles in the brain. Activated microglia, brain‐resident macrophages, are also found surrounding Aβ plaques. The study of the...
作者:Sung Min Son , Hyundong Song ...
来源:[J].Autophagy(IF 12.042), 2012, Vol.8 (12), pp.1842-1844Taylor & Francis
摘要:Alzheimer disease (AD) is sometimes referred to as type III diabetes because of the shared risk factors for the two disorders. Insulin resistance, one of the major components of type II diabetes mellitus (T2DM), is a known risk factor for AD. Insulin resistance increases amy...

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