全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Chairat Uthaipibull , Yongyuth Yuthavong , Sumalee Kamchonwongpaisan
来源:[J].BMC Genomics(IF 4.397), 2015, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)Control of malaria is threatened by emerging parasite resistance to artemisinin and derivative drug (ART) therapies. The molecular detail of how Plasmodium malaria parasites respond to ART and how this could contribute to resistance are not well under...
作者:Sumalee Kamchonwongpaisan , Wachiraporn Tipsuwan
来源:[J].Malaria Journal(IF 3.4), 2015, Vol.14 (1)Springer
摘要:Abstract(#br) Background(#br)Iron is an essential micronutrient required by all living organisms including malaria parasites ( Plasmodium spp.) for many biochemical reactions, especially growth and multiplication processes. Therefore, malaria parasite needs to take up the ir...
作者:... Chayaphat Wongsombat , Porntip Chavalitshewinkoon-Petmitr , Sumalee Kamchonwongpaisan
来源:[J].Malaria Journal(IF 3.4), 2011, Vol.10 (1)Springer
摘要:Abstract(#br) Background(#br)Pyronaridine (PN) and chloroquine (CQ) are structurally related anti-malarial drugs with primarily the same mode of action. However, PN is effective against several multidrug-resistant lines of Plasmodium falciparum , including CQ resistant lines, sug...
作者:Sumalee Kamchonwongpaisan , Yongyuth Yuthavong
来源:[J].Malaria Journal(IF 3.4), 2011, Vol.10 (1)Springer
摘要:Abstract(#br) Background(#br)The prevalence of drug resistance amongst the human malaria Plasmodium species has most commonly been associated with genomic mutation within the parasites. This phenomenon necessitates evolutionary predictive studies of possible resistance mutations,...
作者:... Somdet Srichairatanakool , Yongyuth Yuthavong , Sumalee Kamchonwongpaisan
来源:[J].Malaria Journal(IF 3.4), 2011, Vol.10 (1)Springer
摘要:Abstract(#br) Background(#br) Plasmodium vivax is the most prevalent cause of human malaria in tropical regions outside the African continent. The lack of a routine continuous in vitro culture of this parasite makes it difficult to develop specific drugs for this disease. To faci...
作者:Sumalee Kamchonwongpaisan , Anthony C. Willis ...
来源:[J].Fitoterapia(IF 2.231), 2017, Vol.120, pp.103-107Elsevier
摘要:Abstract(#br)Three new 2-phenylnaphthalene derivatives, cherrevenaphthalenes A–C ( 1–3 ), and a new polyoxygenated cyclohexene derivative, (−)-uvaribonol F ( 4 ) together with six known compounds, 5–10 , were isolated from the stem and root extracts of Uvaria cherrevens...
作者:Sumalee Kamchonwongpaisan , Surat Laphookhieo ...
来源:[J].Fitoterapia(IF 2.231), 2018Elsevier
摘要:Abstract(#br)The phytochemical investigation of the fruit extracts of Uvaria cherrevensis led to the isolation and characterization of four new C-benzyl flavonoids; cherrevenones A-D (1–4) together with 11 known compounds. The isolated compounds were characterized using spec...
作者:Sumalee Kamchonwongpaisan , Stephen J. Blanksby ...
来源:[J].Tetrahedron(IF 2.803), 2019, Vol.75 (15), pp.2336-2342Elsevier
摘要:Abstract(#br)The phytochemical investigation of the leaf extract of Uvaria cherrevensis (Annonaceae) yielded three new cyclohexene (9 Z )-octadec-9-enyl ethers, cherrevenols M-O ( 1 – 3 ), and a known fatty ester derivative ( 4 ). The structures of the isolated compounds wer...
作者:Sumalee Kamchonwongpaisan , Yongyuth Yuthavong
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2019Elsevier
摘要:Abstract(#br)The series of des -Cl (unsubstituted) and m -Cl phenyl analogues of PYR with various flexible 6-substituents were synthesized and studied for the binding affinities with highly resistant quadruple mutant (QM) DHFR. The derivatives carrying 4 atoms linker with a termi...

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