全部文献期刊会议图书|学者科研项目
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作者:Subhasree Nag , Susan R. Crowell
来源:[J].Toxicology Letters(IF 3.145), 2017, Vol.269, pp.23-32
摘要:Abstract(#br)Polycyclic aromatic hydrocarbons (PAHs) are contaminants that are ubiquitously found in the environment, produced through combustion of organic matter or petrochemicals, and many of which are procarcinogens. The prototypic PAH, benzo[a]pyrene (B[a]P) and the hig...
作者:Subhasree Nag , Jiang-Jiang Qin ...
来源:[J].Journal of Chromatography B(IF 2.487), 2014, Vol.969, pp.235-240
摘要:Abstract(#br)In the present study, a specific and sensitive liquid chromatography-triple quadrupole mass spectrometry method was developed and validated for the determination of SP-141, a novel pyrido[b]indole anticancer agent. After a liquid–liquid extraction with n -hexane...
作者:Subhasree Nag , Wei Wang ...
来源:[J].BBA - Reviews on Cancer(IF 9.033), 2014, Vol.1846 (2), pp.297-311
摘要:Abstract(#br)The NFAT signaling pathway regulates various aspects of cellular functions; NFAT acts as a calcium sensor, integrating calcium signaling with other pathways involved in development and growth, immune response, and inflammatory response. The NFAT family of transcripti...
作者:Subhasree Nag , Wei Wang ...
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2013, Vol.68, pp.473-481
摘要:Abstract(#br)Four new sesquiterpenoid dimers (lineariifolianoids E–H, 1 – 4 ), five new sesquiterpenoids ( 5 – 9 ), and seven known sesquiterpenoids ( 10 – 16 ) were isolated from the aerial parts of Inula lineariifolia Turcz. Their structures were determined by spectro...
作者:Subhasree Nag , Su Xu ...
来源:[J].Chinese Journal of Natural Medicines, 2015, Vol.13 (7), pp.554-560
摘要:Abstract(#br)We have recently designed and synthesized several novel iminoquinone anticancer agents that have entered preclinical development for the treatment of human cancers. Herein we developed and validated a quantitative HPLC-MS/MS analytical method for one of the lead nove...
作者:Subhasree Nag , Jiang‐Jiang Qin ...
来源:[J].Biomedical Chromatography(IF 1.945), 2015, Vol.29 (5), pp.654-663
摘要:Abstract(#br)There is an increasing interest in targeting the MDM2 oncogene for cancer therapy. SP‐141, a novel designed small molecule MDM2 inhibitor, exerts excellent in vitro and in vivo anticancer activity. To facilitate the preclinical development of this candidate anti...
作者:Subhasree Nag , Xu Zhang ...
来源:[J].Medicinal Research Reviews(IF 9.583), 2015, Vol.35 (2), pp.225-285
摘要:Abstract(#br)Ribosomes are essential components of the protein synthesis machinery. The process of ribosome biogenesis is well organized and tightly regulated. Recent studies have shown that ribosomal proteins (RPs) have extraribosomal functions that are involved in cell pro...
作者:Subhasree Nag , Jianwei Zhou
来源:[J].Medicinal Research Reviews(IF 9.583), 2015, Vol.35 (6), pp.1220-1267
摘要:Abstract(#br)Polycomb group (PcG) proteins are transcriptional repressors that regulate several crucial developmental and physiological processes in the cell. More recently, they have been found to play important roles in human carcinogenesis and cancer development and progr...

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